Actively Recruiting
Impact of Dietary Fiber Supplementation on Colonic Microbiome
Led by OHSU Knight Cancer Institute · Updated on 2026-01-15
120
Participants Needed
1
Research Sites
195 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial tests whether daily fiber supplementation will change the mucosal microbiome of the colon. The microbiome are microorganisms that live in the human gut. They serve a vital role in maintaining health. Certain microbial strains are associated with the growth of colon polyps, which eventually could go on to form colon cancer. Giving dietary fiber supplements may help prevent precancerous polyps from ever developing.
CONDITIONS
Official Title
Impact of Dietary Fiber Supplementation on Colonic Microbiome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age = 18 years
- Ability to understand and willingness to sign a written informed consent document
- Patients presenting with benign anorectal conditions such as hemorrhoids, anal fissures, or anal fistulas without colorectal cancer or Crohn's disease
- Patients undergoing a standard of care colonoscopy procedure
You will not qualify if you...
- Active malignancy, Crohn's disease, ulcerative colitis, or immunosuppressed status
- Hereditary colon cancer syndromes including Lynch syndrome or Familial Adenomatous Polyposis (FAP)
- Prior history of total or partial colon resection
- Presence of colorectal pathology such as cancer or proctitis after initial study scope
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
OHSU Knight Cancer Institute
Portland, Oregon, United States, 97239
Actively Recruiting
Research Team
S
Shahrose Rahman, M.D.
CONTACT
A
Amber O'Connor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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