Impact of Discontinuing Contact Precautions for Extended-spectrum Beta-lactamase Enterobacteriaceae in a Geriatric Unit: An Interventional Prospective Noninferiority Double-blind Controlled Before and After Study

What this Trial Is About

Researchers are evaluating whether stopping contact precautions is as safe as continuing them in preventing infections caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in older adults hospitalized in geriatric units. This study is designed as a prospective, non-randomized, double-blind controlled before and after study to compare infection rates before and after discontinuing contact precautions. The study addresses a significant concern as these infections are common in healthcare settings and limit treatment options. Participants will be observed during two study phases: one with the use of contact precautions alongside standard precautions for patients carrying ESBL-producing bacteria, and another phase after stopping contact precautions where only standard precautions are used. The study involves comparing the incidence density of acquired ESBL infections over a six-month period in a geriatric hospital setting. Throughout the study, participants' infection status will be monitored and healthcare workers' compliance with hand hygiene and protective equipment use will be assessed. Patient satisfaction related to care will also be evaluated using questionnaires at discharge. This monitoring includes safety evaluations and adherence tracking, with follow-up assessments conducted during and after the six-month observation periods.

Impact of Discontinuing Contact Precautions for Extended-spectrum β-lactamase Enterobacteriaceae in a Geriatric Unit