Study on How a Dried Chicory Root Fiber Product Affects Bowel Function and Gut Microbiota in Adults With Bowel Issues

What this Trial Is About

Researchers are evaluating the effects of a dried multifiber vegetable product on bowel function and gut microbiota in adults aged 20 to 80 who are dissatisfied with their current bowel function. This randomized, placebo-controlled, parallel, double-blind trial aims to understand whether this high-fiber dried vegetable can improve stool frequency, consistency, ease of defecation, feelings of incomplete bowel emptying, and overall bowel function satisfaction. The study also explores if these effects depend on the dose and how bowel function and gut microbiota adapt over time. Participants are randomly assigned to one of four groups three receive different doses of dried chicory root particles 5g, 10g, or 15g per day in two portions, and one group receives a placebo of rice puff particles. All are consumed twice daily with food for four weeks. The intervention product contains about 85% dietary fiber. The placebo matches the medium fiber doses calorie content. The study examines differences between the highest dose and placebo, as well as dose-dependent effects across groups. During the study, participants will undergo assessments of bowel function through stool frequency, consistency, ease of defecation, feelings of incomplete emptying, and satisfaction. Researchers will also analyze stool samples to study gut microbiota composition and activity. Questionnaires on quality of life and constipation symptoms are included. The main outcomes focus on changes after four weeks of intervention. Participants adherence and safety will be monitored throughout the study period, which lasts four weeks from intervention start to completion.

Impact of a Dried Vegetable on Bowel Function and Gut Microbiota