Actively Recruiting
Impact of Dry vs Humidified Culture Conditions on Blastocyst Development and Aneuploidy: A Time-lapse Sibling Oocyte Study
Led by ART Fertility Clinics LLC · Updated on 2026-05-07
60
Participants Needed
1
Research Sites
98 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
IVF incubators are essential for maintaining the micro-environment required for embryo development. Incubator technology has progressed from early humidified box systems to benchtop and now time-lapse platforms, driving the development of dry incubator chambers. Both humidified and dry systems have specific pros and cons. Evidence to date suggests that humidified chambers may support better blastocyst development in certain "no-refresh" continuous culture conditions, but current data are limited and study designs remain weak. This study aims to compare sibling oocytes cultured in dry versus humidified chambers within a GERI time-lapse incubator under continuous culture conditions, assessing effects on viability and developmental outcomes. Findings may inform optimal incubation strategies to improve IVF success rates while supporting uninterrupted workflows and potentially improving cost-benefit efficiency in the IVF laboratory.
CONDITIONS
Official Title
Impact of Dry vs Humidified Culture Conditions on Blastocyst Development and Aneuploidy: A Time-lapse Sibling Oocyte Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- PGT-A cycles with at least 4 mature oocytes
- Use of intracytoplasmic sperm injection (ICSI)
- Maternal age between 18 and 43 years old
- Intended PGT-A cycles with trophectoderm biopsies on day 5, 6, or 7
- Expected retrieval of more than 8 oocytes for ICSI
- Body mass index (BMI) less than 35
- Use of fresh or frozen ejaculated sperm
You will not qualify if you...
- PGT-M or PGT-SR cycles
- Use of fresh or frozen testicular sperm
- IVF insemination cycles
- Previous history of fertilization failure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
ART Fertility Clinics LLC
Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates, 60202
Actively Recruiting
Research Team
J
JONALYN EDADES, EMBA Healthcare Management
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
OTHER
Number of Arms
2
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