Actively Recruiting

Age: 12Years +
All Genders
NCT07467564

The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis

Led by Sanofi · Updated on 2026-05-14

184

Participants Needed

2

Research Sites

64 weeks

Total Duration

On this page

Sponsors

S

Sanofi

Lead Sponsor

R

Regeneron Pharmaceuticals

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to assess the impact of dupilumab on the mental health and quality of life of moderate-to-severe Atopic Dermatitis (AD) patients. The study will recruit participants from AD patients who are already receiving dupilumab treatment. The study enrollment period will be about 9 months with each of the participants undergoing a 6-month observational study period.

CONDITIONS

Official Title

The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis

Who Can Participate

Age: 12Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants who have moderate to severe AD with signs and symptoms of anxiety and/or depression.
  • Participants who initiate dupilumab therapy within 30 days of enrolment, based on the treating physician's decision, independently of study participation
  • Participants and/or their legally approved representatives (LAR in case of the minor subject) must agree to sign an informed consent or an assent.
Not Eligible

You will not qualify if you...

  • Females who are pregnant, lactating, or planning/intending to be pregnant in the next 6 months.
  • Participants who are participating in another trial.
  • Participants with active chronic or acute infection requiring systemic treatment.
  • Participants who are diagnosed with active endoparasite infection or are suspected of being at high risk of infection.
  • Participants with human immunodeficiency virus (HIV), hepatitis B or C, malignancy, or other concomitant illnesses.
  • Participants on antidepressants/anti-anxiety within 6 months of enrolment or those who are planning to receive antidepressants/anti-anxiety. In addition, those who will use antidepressants/anti-anxiety medications throughout the study will be excluded from the analysis.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Saudi Medical Services (Medical Fakeeh)

Jeddah, Saudi Arabia, 21331

Actively Recruiting

2

NMC Specialty Hospital LTD

Abu Dhabi, United Arab Emirates

Actively Recruiting

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Research Team

T

Trial Transparency email recommended (Toll free for US & Canada)

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis | DecenTrialz