Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
All Genders
Healthy Volunteers
NCT06398548

Impact of Exercise Intensity on Fitness, Extracellular Vesicles, Inflammation, and Metabolism

Led by University of British Columbia · Updated on 2024-05-08

50

Participants Needed

1

Research Sites

95 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Introduction This study investigates the effects of different intensities of indoor cycling on various health measures. Participants will perform a maximal cycling test to determine their maximal fitness - a strong predictor of overall health - before and after a 6-week training intervention. Blood samples will also be obtained to look at various physiological markers related to extracellular vesicles, inflammation, and metabolism. Who can participate? Healthy young adults who between 18 and 40, are free of immune disease, with a normal body mass index can join this study. They will be divided into three groups: * One group will ride a bike at a moderate pace. * Another group will ride a bike at a slightly harder pace. * The third group won't change their usual daily activities and will continue living as they normally do. What does the study involve? Each exercise session aims to burn a specific amount of calories: 350 for males and 300 for females. Participants cycle 3 times a week for 6 weeks. At the end, we'll repeat the bike test and take another blood sample to see if there have been any changes due to the exercise. Why is this research being done? The researchers want to see how different intensities of exercise impact health and fitness. This may help people make better choices about how much and what type of exercise they should do. What happens after the study? Researchers will analyze the data from the study and see if any differences exist between the protocols. If the participant is interested, we will also provide their blood test results, and the results from their max test.

CONDITIONS

Official Title

Impact of Exercise Intensity on Fitness, Extracellular Vesicles, Inflammation, and Metabolism

Who Can Participate

Age: 18Years - 40Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Between 18 and 40 years old
  • Body mass index (BMI) between 18.5 and 30 kg/m²
  • Perform 60 to 200 minutes of aerobic physical activity per week
  • No history of cardiovascular disease or diabetes
Not Eligible

You will not qualify if you...

  • Use immunomodulatory medication for autoimmune disease or rely heavily on over-the-counter anti-inflammatory medications
  • Have a metabolic condition such as diabetes
  • Have high blood pressure above 160/90 mmHg
  • Are uncomfortable with blood sampling
  • Are elite endurance athletes or training for endurance events with more than 3 aerobic sessions or over 150 minutes of endurance training per week
  • Follow an extreme diet like ketogenic or time-restricted feeding
  • Smoke cigarettes

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

ART 115

Kelowna, British Columbia, Canada, V1V 1V7

Actively Recruiting

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Research Team

J

Jonathan P Little, PhD

CONTACT

G

Garett S Jackson, MSc.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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