Actively Recruiting
Impact of Exercise Intensity on Fitness, Extracellular Vesicles, Inflammation, and Metabolism
Led by University of British Columbia · Updated on 2024-05-08
50
Participants Needed
1
Research Sites
95 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Introduction This study investigates the effects of different intensities of indoor cycling on various health measures. Participants will perform a maximal cycling test to determine their maximal fitness - a strong predictor of overall health - before and after a 6-week training intervention. Blood samples will also be obtained to look at various physiological markers related to extracellular vesicles, inflammation, and metabolism. Who can participate? Healthy young adults who between 18 and 40, are free of immune disease, with a normal body mass index can join this study. They will be divided into three groups: * One group will ride a bike at a moderate pace. * Another group will ride a bike at a slightly harder pace. * The third group won't change their usual daily activities and will continue living as they normally do. What does the study involve? Each exercise session aims to burn a specific amount of calories: 350 for males and 300 for females. Participants cycle 3 times a week for 6 weeks. At the end, we'll repeat the bike test and take another blood sample to see if there have been any changes due to the exercise. Why is this research being done? The researchers want to see how different intensities of exercise impact health and fitness. This may help people make better choices about how much and what type of exercise they should do. What happens after the study? Researchers will analyze the data from the study and see if any differences exist between the protocols. If the participant is interested, we will also provide their blood test results, and the results from their max test.
CONDITIONS
Official Title
Impact of Exercise Intensity on Fitness, Extracellular Vesicles, Inflammation, and Metabolism
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between 18 and 40 years old
- Body mass index (BMI) between 18.5 and 30 kg/m²
- Perform 60 to 200 minutes of aerobic physical activity per week
- No history of cardiovascular disease or diabetes
You will not qualify if you...
- Use immunomodulatory medication for autoimmune disease or rely heavily on over-the-counter anti-inflammatory medications
- Have a metabolic condition such as diabetes
- Have high blood pressure above 160/90 mmHg
- Are uncomfortable with blood sampling
- Are elite endurance athletes or training for endurance events with more than 3 aerobic sessions or over 150 minutes of endurance training per week
- Follow an extreme diet like ketogenic or time-restricted feeding
- Smoke cigarettes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
ART 115
Kelowna, British Columbia, Canada, V1V 1V7
Actively Recruiting
Research Team
J
Jonathan P Little, PhD
CONTACT
G
Garett S Jackson, MSc.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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