Actively Recruiting
The Impact of Fexofenadine Hydrochloride on the Prognosis of Patients Post-Acute Myocardial Infarction
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2026-02-02
2804
Participants Needed
1
Research Sites
122 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is o evaluate the prognostic effect of fexofenadine hydrochloride in patients with myocardial infarction
CONDITIONS
Official Title
The Impact of Fexofenadine Hydrochloride on the Prognosis of Patients Post-Acute Myocardial Infarction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 63 18 years old
- Able to verbally confirm understanding of the trial risks, benefits, and treatment options of fexofenadine hydrochloride therapy and provide written informed consent
- Acute ST-segment elevation myocardial infarction (STEMI) within 7 days, with typical clinical symptoms, elevated serum cardiac troponin, and new ST-segment elevation in 2 adjacent leads
- Echocardiography showing segmental wall motion abnormalities
You will not qualify if you...
- Need for long-term use of fexofenadine hydrochloride or other H1 receptor inhibitors
- Previous coronary artery bypass grafting (CABG) surgery
- History of severe renal failure with eGFR < 30 ml/min
- History of severe liver dysfunction
- History of severe infection, hepatobiliary obstruction, or malignant tumor
- Expected life expectancy less than 2 years due to non-cardiac diseases
- Currently receiving immunosuppressive therapy
- Pregnant, potentially pregnant, or lactating women
- Contraindication to the study drug or examinations
- Failure to provide written informed consent
- Presence of mechanical complications, refractory cardiogenic shock, acute left heart failure, pulmonary edema, or uncontrolled malignant arrhythmias at enrollment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Second Affiliated Hospital of Zhejiang University, School of Medicine
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
C
Cheng Ni
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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