Actively Recruiting

Phase 3
Age: 18Years - 80Years
All Genders
NCT05916963

Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser

Led by University Hospital, Tours · Updated on 2025-11-24

374

Participants Needed

9

Research Sites

117 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In view of the positive results of the numerous studies conducted on forced diuresis after extra-corporeal lithotripsy, the investigators chose to evaluate forced diuresis by injection of Furosemide associated with intravenous hydration, which has never before been the subject of a specific analysis.

CONDITIONS

Official Title

Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients 18 years old and under 80 years old
  • Need to undergo flexible ureteroscopy with laser destruction of kidney stones
  • Covered by or entitled to social security
  • Provided written informed consent
  • Able to follow study requirements
Not Eligible

You will not qualify if you...

  • Pregnant women, breastfeeding mothers, minors, persons under legal protection, or deprived of liberty
  • Allergy or sensitivity to Furosemide or sulfonamides
  • Renal failure with oligo-anuria unresponsive to Furosemide
  • Low potassium levels (hypokalemia < 3.5 mmol/L)
  • Severe low sodium levels (hyponatremia)
  • Low blood volume or dehydration, with or without low blood pressure
  • Severe liver disease or ongoing hepatitis
  • Currently taking Furosemide regularly
  • Need for Aminoside or Vancomycin injection before or during procedure
  • Participation in other interventional research involving drugs or medical devices

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 9 locations

1

CHU d'Angers

Angers, France

Actively Recruiting

2

Hospices Civils de Lyon

Lyon, France

Actively Recruiting

3

CHU de Nice

Nice, France

Actively Recruiting

4

CHU de Nîmes

Nîmes, France

Actively Recruiting

5

CHU de Rennes

Rennes, France

Actively Recruiting

6

CHU de Rouen

Rouen, France

Actively Recruiting

7

CHU de Toulouse

Toulouse, France

Actively Recruiting

8

Clinique La Croix du Sud

Toulouse, France

Actively Recruiting

9

CHRU de Tours

Tours, France

Actively Recruiting

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Research Team

M

Marie-Lou LETOUCHE, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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