Actively Recruiting

Age: 14Years - 50Years
All Genders
NCT05885048

Impact of Gonadotoxic Therapies on Fertility

Led by Michael von Wolff · Updated on 2024-06-03

7000

Participants Needed

1

Research Sites

787 weeks

Total Duration

On this page

Sponsors

M

Michael von Wolff

Lead Sponsor

U

University of Bern

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to learn how gonadotoxic treatments (chemotherapies, radiotherapies or immunotherapies) affect the fertility status of participants with cancer. The main questions it aims to answer are: * in females, if cancer therapies reduce the Anti-Müllerian hormone (AMH) concentration (ovarian reserve); * in males, if cancer therapies reduce sperm concentration (sperm quality).

CONDITIONS

Official Title

Impact of Gonadotoxic Therapies on Fertility

Who Can Participate

Age: 14Years - 50Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with cancer or benign condition and scheduled for chemotherapy and/or radiotherapy of the pelvis (females) or testicles (males) and/or immunotherapy
  • Willing to participate in the study
  • Aged 14 to 50 years in Austria and Switzerland, aged 18 to 50 years in Germany
  • Have serum hormone analysis before gonadotoxic therapy (for females)
  • Have serum hormone analysis and sperm analysis before gonadotoxic therapy (for males)
Not Eligible

You will not qualify if you...

  • Missing consent to participate
  • Language barrier preventing study participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Women's Hospital (Inselspital)

Bern, Switzerland, 3010

Actively Recruiting

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Research Team

M

Michael von Wolff, Prof. Dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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