Actively Recruiting
Impact of Gravity on Cardiac Hemodynamics
Led by University Hospital, Caen · Updated on 2025-03-26
32
Participants Needed
1
Research Sites
99 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Caen
Lead Sponsor
I
INSERM UMR-S 1075 COMETE, Caen, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to define and compare pre-load dependance of the cardiac function according to the intracardiac hydrostatic gradient of pressure in healthy and diabetic populations. Participants will undergo 4 tilt angle and 4 lower body negative pressure intensities during which cardiovascular data will be assessed and a transthoracic echography will be performed.
CONDITIONS
Official Title
Impact of Gravity on Cardiac Hemodynamics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Affiliated to the social security system
- Patient informed of the study and having signed an informed consent form
- Type 1 diabetes for at least 10 years followed at Caen University Hospital, equipped with a continuous glucose monitoring system
You will not qualify if you...
- Trained athletes (6 or more hours of sustained physical exercise >70% VO2max per week for more than 6 months)
- Chronic cardiovascular disease or cardiovascular treatment
- Personal history of chemotherapy and/or thoracic radiotherapy
- Cerebral and/or spinal disease
- Participation in another interventional biomedical research protocol during the study or within 3 months prior
- Pregnant, breast-feeding, or parturient women
- Adults under legal protection or unable to consent or deprived of their freedom
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Inserm 1075 Comete, Unicaen
Caen, France, 14000
Actively Recruiting
Research Team
A
Amir HODZIC, MD PhD
CONTACT
H
Hervé NORMAND, MD PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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