Actively Recruiting

Phase Not Applicable
Age: 50Years - 75Years
All Genders
Healthy Volunteers
NCT06516146

Impact 360 for Healthy Agers

Led by University of British Columbia · Updated on 2026-03-23

60

Participants Needed

1

Research Sites

206 weeks

Total Duration

On this page

Sponsors

U

University of British Columbia

Lead Sponsor

T

The Jack and Darlene Poole Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The Impact 360 study will evaluate the effects of a combined intervention of exercise, mindfulness, and nutrition on 8 key indicators of health and the mechanisms that drive these changes. 60 subjects aged 50 to 75 without a current diagnosis of a brain disorder will be recruited. This study will follow a partial crossover design. All participants will receive the intervention. Participants randomized into the intervention group after their baseline screening will receive the 6-month intervention. Those randomized into the waitlist group will complete another assessment at the end of the 6-month care as usual phase before receiving the intervention.

CONDITIONS

Official Title

Impact 360 for Healthy Agers

Who Can Participate

Age: 50Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Able to complete questionnaires and follow intervention instructions
  • Access to a smartphone that can support the Fitbit app
  • Age between 50 and 75 years
  • No current diagnosis of a brain disorder
Not Eligible

You will not qualify if you...

  • Diagnosis of neurological diseases such as Parkinson's Disease, Multiple Sclerosis, Traumatic Brain Injury, brain lesion, or stroke
  • Chronic medical conditions affecting exercise ability
  • Contraindications for exercise according to PAR-Q+ and medical clearance
  • Medical requirement for supervised exercise
  • Montreal Cognitive Assessment (MoCA) score below 21/30
  • Significant cognitive impairment, depression, or eating disorder
  • Contraindications to MRI scanning including implanted metal devices or recent surgery
  • Currently doing 180 minutes or more of moderate-vigorous exercise per week and either completed Mindfulness-Based Stress Reduction course or high MIND diet score
  • Significant or unstable cardiovascular or respiratory diseases
  • Severe or multiple head trauma
  • Pregnancy or breastfeeding
  • History of major drug or alcohol abuse
  • Chronic or acute infections
  • Gastrointestinal cancer or inflammatory bowel disease
  • Body weight over 400 lbs (MRI limit)
  • Presence of artificial heart valve, brain aneurysm clip, electrical nerve/bone stimulator, ear or eye implants, drug infusion pump, blood vessel coils or filters, orthopedic hardware, metallic prostheses, shrapnel or metal fragments
  • Recent surgery or tattoos within six weeks
  • Brain surgery history
  • Cardiac pacemaker, wires, or defibrillator
  • Eye or orbit metal injury
  • Ferromagnetic aneurysm clip

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of British Colombia

Vancouver, British Columbia, Canada, V6T 1Z3

Actively Recruiting

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Research Team

J

Jeffrey Kelly, MSc

CONTACT

A

Annie Kuan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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