Actively Recruiting
Impact of IBD Activity on Frailty in Patients Over 60 Years
Led by Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa · Updated on 2026-05-07
153
Participants Needed
34
Research Sites
106 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational, multicenter, descriptive, prospective, and longitudinal study is to evaluate the impact of IBD activity on frailty in a prospective and longitudinal cohort of patients with IBD, and also to assess the impact of frailty on the risk of hospitalization and mortality in patients with IBD aged ≥60 years. The main questions it aims to answer are: 1. Can frailty and consequently the risk of complications (adverse events, hospitalization, and mortality) be reversed through proactive treatment in frail patients with active inflammatory bowel disease? 2. Which frailty index is the most effective for predicting the risk of complications in patients with active inflammatory bowel disease? At inclusion, clinical frailty indices will be calculated. Additionally, clinical variables related to IBD and comorbidities will be recorded. During follow ups visits frailty, comorbidities, IBD activity, changes in medical treatment for IBD, adverse effects, hospitalizations, and mortality will be reassessed.
CONDITIONS
Official Title
Impact of IBD Activity on Frailty in Patients Over 60 Years
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 60 years or older with inflammatory bowel disease (Crohn's disease or ulcerative colitis) diagnosed by ECCO criteria and followed in participating IBD units
- Starting medical treatment (oral mesalazine, topical or systemic corticosteroids, immunosuppressants, and/or biologics) due to active disease based on clinical symptoms or biological markers
- Signed informed consent for participation
You will not qualify if you...
- Lack or withdrawal of informed consent
- Diagnosis of unclassified or indeterminate colitis
- Change in medical treatment only because of adverse events
- Starting treatment only with salicylates and/or topical steroids for disease activity
- Treatment intensification used to manage disease activity
- Presence of an ostomy
- Comorbidities with life expectancy less than one year
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 34 locations
1
Hospital Universitario Araba
Vitoria-Gasteiz, Alava, Spain, 01009
Actively Recruiting
2
Hospital Germans Trias i Pujol
Badalona, Barcelona, Spain
Actively Recruiting
3
Hospital de Bellvitge
L'Hospitalet de Llobregat, Barcelona, Spain
Actively Recruiting
4
Althaia Manresa
Manresa, Barcelona, Spain
Actively Recruiting
5
Hospital del Mataró
Mataró, Barcelona, Spain
Actively Recruiting
6
Consorci Sanitari de Terrassa
Terrassa, Barcelona, Spain
Actively Recruiting
7
Hospital Mútua de Terrassa
Terrassa, Barcelona, Spain
Actively Recruiting
8
Hospital Viladecans
Viladecans, Barcelona, Spain
Actively Recruiting
9
Hospital Sierrallana de Torrelavega
Torrelavega, Cantabria, Spain
Actively Recruiting
10
Hospital de Toledo
Toledo, Castille-La Mancha, Spain
Actively Recruiting
11
Hospital Universitario de Gran Canaria Doctor Negrín
Las Palmas de Gran Canaria, Las Palmas, Spain
Actively Recruiting
12
Hospital de Henares
San Sebastián de los Reyes, Madrid, Spain
Actively Recruiting
13
Hospital San Agustín de Avilés
Avilés, Principality of Asturias, Spain
Actively Recruiting
14
Hospital de Cabueñes
Gijón, Principality of Asturias, Spain
Actively Recruiting
15
Hospital Universitario Central de Astúrias
Oviedo, Principality of Asturias, Spain
Actively Recruiting
16
Hospital Universitario de Canarias
San Cristóbal de La Laguna, Santa Cruz De Tenerife, Spain
Actively Recruiting
17
Hospital Dr Balmis
Alicante, Valencia, Spain
Actively Recruiting
18
Hospital Denia
Denia, Valencia, Spain
Actively Recruiting
19
Hospital Royo Villanova
San Gregorio, Zaragoza, Spain
Actively Recruiting
20
Complejo Asistencial de Ávila
Ávila, Spain
Actively Recruiting
21
Hospital de la Santa Creu i Sant Pau
Barcelona, Spain
Actively Recruiting
22
Hospital Universitario de Burgos
Burgos, Spain
Actively Recruiting
23
Hospital Universitari Dr Josep Trueta
Girona, Spain
Actively Recruiting
24
Hospital Juan Ramón Jiménez
Huelva, Spain
Actively Recruiting
25
Hospital Universitario Lucus Augusti
Lugo, Spain
Actively Recruiting
26
Hospital Infanta Elena
Madrid, Spain, 28342
Actively Recruiting
27
Hospital Puerta de Hierro Majadahonda
Madrid, Spain
Actively Recruiting
28
Hospital Ramon y Cajal
Madrid, Spain
Actively Recruiting
29
Hospital Universitario Infanta Leonor
Madrid, Spain
Actively Recruiting
30
Complexo Hospitalario Universitario de Ourense
Ourense, Spain
Actively Recruiting
31
Hospital Universitario Ntra. Sra. de Candelaria
Santa Cruz de Tenerife, Spain
Actively Recruiting
32
Hospital General Universitario de Valencia
Valencia, Spain
Actively Recruiting
33
Hospital Universitario de la Fe
Valencia, Spain
Actively Recruiting
34
Hospital Lozano Blesa
Zaragoza, Spain
Actively Recruiting
Research Team
E
Erika Araya
CONTACT
A
Anna Casas
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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