Actively Recruiting

Age: 18Years +
All Genders
NCT07508007

Impact of Implementation Strategies on Lp(a) Testing in Secondary Care Settings

Led by Novartis Pharmaceuticals · Updated on 2026-04-02

4500

Participants Needed

1

Research Sites

122 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Lipoprotein(a) \[Lp(a)\] is recognised as an independent, non-modifiable genetic risk factor for cardiovascular (CV) disease. Current guidelines from the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS) recommend that Lp(a) be measured at least once in every adult's lifetime, however routine Lp(a) testing rates remains infrequent. The aim of this study is to assess the impact of implementation strategies (IStr) designed to increase the adoption of Lp(a) testing in routine practice, ultimately leading to more individuals being tested in secondary care. This, in turn, is expected to result in the identification and enhanced management of Cardiovascular Disease (CVD) risk patients with elevated Lp(a).

CONDITIONS

Official Title

Impact of Implementation Strategies on Lp(a) Testing in Secondary Care Settings

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Lp(a) testing is available and reimbursed at the healthcare center
  • Center can increase Lp(a) testing rates among eligible patients
  • Current Lp(a) testing rate at center is less than 15% for eligible patients
  • Willingness to fulfill research requirements such as repurposing clinic data
  • Center sees a defined number of eligible patients per year for study sample size
  • Local infrastructure and data interoperability are available
  • Healthcare professionals are cardiovascular specialists or manage cardiovascular risk at their centers
  • Patients are over 18 years old and qualify for Lp(a) testing according to local practice
  • Patients attend at least one secondary care visit during specified study periods
  • Informed consent or waiver obtained before using electronic patient records
Not Eligible

You will not qualify if you...

  • Centers without access to Lp(a) testing
  • Centers where Lp(a) testing is not reimbursed
  • Patients who have undergone Lp(a) testing before the study start for post-implementation assessments

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Novartis Investigative Site

Nuremberg, Germany, 90443

Actively Recruiting

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Research Team

N

Novartis Pharmaceuticals

CONTACT

N

Novartis Pharmaceuticals

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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