Actively Recruiting
Impact of Intensive Computerized Cognitive Training
Led by Brigham and Women's Hospital · Updated on 2025-11-05
30
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
Sponsors
B
Brigham and Women's Hospital
Lead Sponsor
F
Fujifilm
Collaborating Sponsor
AI-Summary
What this Trial Is About
To investigate factors that predict cognitive enhancement following engagement in an intensive Computerized Cognitive Training Protocol.
CONDITIONS
Official Title
Impact of Intensive Computerized Cognitive Training
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient of the Mass General Brigham Health System with primary attention and executive functioning difficulties and/or a diagnosis of mild cognitive disorder or mild neurocognitive disorder (non-amnestic profile), due to an acquired brain injury sustained at least 12 months prior
- Ages 25 to 65 years old
- Proficiency in English
- Willing and able to complete all study activities for 12 months, including travel to Brigham and Women's Hospital for four in-person assessments and two sample collections
- Access to a computer with webcam and stable internet
- Has a reliable study informant who can complete one questionnaire about cognition and daily functioning at four time points
You will not qualify if you...
- History of alcohol or substance abuse or dependence within the past 2 years
- High likelihood of an underlying progressive neurodegenerative disorder
- Moderate to severe cognitive disorder with Mini-Mental Status Examination score of 21 or less
- Patient Health Questionnaire-9 score 19 or higher unless active depression is ruled out by provider
- Active psychotic symptoms
- Severe sensory losses preventing study participation even with accommodations
- Communication difficulties preventing effective participation
- Current participation in other pharmacological or interventional research trials
- Life expectancy less than 2 years
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
G
George-Ryan Ghorayeb, MA
CONTACT
K
Kayla M Riera, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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