Actively Recruiting

Age: 18Years +
All Genders
NCT07324694

Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac Surgery

Led by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital · Updated on 2026-01-12

230

Participants Needed

1

Research Sites

40 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Intraoperative hemodynamic instability (IOHI) is a common occurrence during cardiac surgery and is associated with organ hypoperfusion. However, the specific impact of IOHI on composite adverse outcomes remains unclear. This prospective cohort study aims to evaluate the association between intraoperative hemodynamic instability (defined as MAP \< 65 mmHg or vasopressor requirement) and major postoperative complications (Delirium, Acute Kidney Injury, Stroke, or Mortality) in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass.

CONDITIONS

Official Title

Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older.
  • Scheduled for elective cardiac surgery including coronary artery bypass grafting, valve replacement or repair, or combined procedures.
  • Surgery performed using cardiopulmonary bypass.
  • Preoperative sinus rhythm.
  • Signed informed consent form.
Not Eligible

You will not qualify if you...

  • Emergency or salvage cardiac surgery.
  • Off-pump coronary artery bypass grafting.
  • Requirement for mechanical circulatory support before surgery such as intra-aortic balloon pump or extracorporeal membrane oxygenation.
  • Pre-existing chronic kidney failure requiring hemodialysis or peritoneal dialysis.
  • Pre-existing cognitive impairment, dementia, or psychiatric disorders that affect cooperation.
  • Pregnancy.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Gazi Yaşargil Training and Research Hospital

Diyarbakır, Diyarbakır, Turkey (Türkiye), 21070

Actively Recruiting

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Research Team

O

Osman Uzundere, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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