Impact of Intraoperative Hemodynamic Instability on Postoperative Major Adverse Events in Cardiac Surgery Patients: A Prospective Cohort Study

What this Trial Is About

This research aims to evaluate the impact of intraoperative hemodynamic instability during elective cardiac surgery on major postoperative complications in adults. The study focuses on patients undergoing procedures such as coronary artery bypass grafting or valve replacement/repair with cardiopulmonary bypass. Researchers want to understand how periods of low blood pressure or the need for vasopressors during surgery relate to outcomes like delirium, kidney injury, stroke, or death within 30 days after surgery. Patients will be divided into two groups based on their intraoperative blood pressure: those who experience hemodynamic instability, defined as a mean arterial pressure below 65 mmHg for over 5 minutes or requiring medication support, and those who remain stable without significant hypotension or vasopressor use. The study will record detailed intraoperative heart rate, blood pressure, and medication use to categorize these groups. Participants will be closely monitored for up to 30 days after surgery for adverse events including delirium, acute kidney injury, stroke, and mortality. Researchers will also track secondary outcomes such as the length of mechanical ventilation, ICU stay, and total hospital stay. Data collection includes clinical assessments, monitoring of vital signs, and recording medication use. This observational study aims to better define blood pressure management during cardiac surgery to improve patient recovery.

Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac Surgery