Actively Recruiting
Impact of Intraoperative Non-invasive Analgesia Monitoring Using Nociception Level Index on Patient Management
Led by Osoian Cristiana · Updated on 2025-02-03
160
Participants Needed
1
Research Sites
141 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective randomised clinical trial aims to assess the impact of intraoperative nociception monitoring using NOL on anesthetic management during major abdominal surgery. Additionally, the study will objectively evaluate using NOL how intravenous lidocaine administration, influences opioid requirements and the effect of this multimodal approach on early postoperative outcomes. The investigators hypothesize that NOL-guided intraoperative opioid administration reduces both intraoperative and postoperative opioid use, positively influencing 24-hour outcomes. Furthermore, the addition of intraoperative lidocaine in NOL-guided analgesia may further decrease opioid consumption.
CONDITIONS
Official Title
Impact of Intraoperative Non-invasive Analgesia Monitoring Using Nociception Level Index on Patient Management
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years
- ASA score I to III
- Surgery planned for gastric, hepatobiliary, or pancreatic cancer
You will not qualify if you...
- Pregnancy
- Lactation
- Use of neuraxial or regional anesthesia
- Chronic treatment with drugs affecting the autonomic nervous system
- Use of diuretics or nitroglycerin on the day of surgery
- Severe neurological disability
- Severe hemodynamic instability
- Chronic pain
- Chronic opioid treatment
- Allergy to any study drugs
- Severe untreated disease or organ failure
- Presence of pacemaker
- Emergency surgery
- Patient refusal to participate
AI-Screening
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Trial Site Locations
Total: 1 location
1
Regional Gastroenterology and Hepatology Institute Octavian Fodor
Cluj-Napoca, Cluj, Romania
Actively Recruiting
Research Team
C
Cristiana Osoian
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
4
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