Evaluating Irrisept Instillation Compared to Saline to Reduce Urinary Tract Infection After Catheter Removal

What this Trial Is About

This research aims to evaluate the use of Irrisept instillation as a non-antibiotic approach to reduce urinary tract infections UTIs after urethral catheter removal. The study focuses on comparing antiseptic bladder irrigation using 0.05% chlorhexidine gluconate against normal saline irrigation, aiming to provide important insights into preventing UTIs while minimizing antibiotic use. Successful results may influence new clinical guidelines for catheter removal protocols to improve patient outcomes and reduce healthcare costs. Participants are randomly assigned to receive either bladder instillation with 0.05% chlorhexidine gluconate or normal saline before attempting to void after catheter removal. The study involves two groups a standard care group receiving saline irrigation and an experimental group receiving the antiseptic solution. Both treatments are instilled into the bladder prior to trial of void, with no blinding involved in the allocation. During the study, participants are monitored for urinary tract infections, antibiotic use, and any adverse events over a 30-day period following catheter removal. Participants will complete a post-catheter removal survey to capture relevant data. The study is led by Ohio State University and includes adults aged 18 and older attending a urology clinic for catheter removal. Overall participation lasts at least 30 days to assess infection rates and treatment safety.

The Impact of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.