Effects of Laparotomy and Pain Relief Methods on Diaphragm Muscle Function Following Major Abdominal Surgery

What this Trial Is About

Researchers are investigating how major abdominal surgeries performed through laparotomy and different pain relief methods affect diaphragm muscle function. The study focuses on patients undergoing major abdominal surgery, aiming to understand how surgery and analgesia impact diaphragm thickness and contraction. This observational study uses ultrasonography to measure these effects during the early postoperative period. Participants will undergo ultrasonography to measure diaphragm muscle thickness at the xiphoid level before surgery and one hour after surgery. Measurements are taken in the supine position during inspiration, expiration, and forced inspiration. The study evaluates how various analgesia methods, including intravenous drugs, epidural catheters, and abdominal plane blocks, influence diaphragm contraction after laparotomy. During the study, participants will have diaphragm thickness assessed using ultrasound before and after surgery. Researchers will monitor the impact of surgery and pain relief on diaphragm function by comparing measurements taken at the first postoperative hour. The main outcome measured is the change in diaphragm thickness, with additional evaluation of analgesia effects. The study is expected to complete in August 2025, with participant involvement spanning the perioperative period and immediate postoperative assessments.

The Impact of Laparotomy and Analgesia Methods on Diaphragm