Actively Recruiting
The Impact of Melatonin Lotion on Sleep and Mental Health
Led by University of Redlands · Updated on 2026-05-01
60
Participants Needed
1
Research Sites
161 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to examine the effect that melatonin lotion has on sleep quality, the nervous system, and mental health. Melatonin is a hormone secreted by the brain that regulates sleep and might improve depression and anxiety symptoms. The goal is to determine whether melatonin in lotion form is an effective treatment for young adults with inadequate sleep and might improve mental health. Participants will fill out surveys, wear an actigraph (a wrist-worn device that measures sleep), wear a heart rate monitor (a strap worn around one's chest), and provide nightly saliva samples during treatment weeks. In one of the two treatment weeks, participants will receive a lotion that contains melatonin. During the other week they will receive a control treatment that will be lotion with no melatonin, and there will be a week in between with no treatment at all.
CONDITIONS
Official Title
The Impact of Melatonin Lotion on Sleep and Mental Health
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have a T score of 48 or higher on the PROMIS sleep disturbance short form
- Have a T score of 55 or higher on the PROMIS anxiety or depression short form (mild symptoms or more)
- Are between 18 and 21 years old
- Are willing to keep a consistent bedtime (within ±1 hour) during treatment weeks
- Are able to apply lotion and complete study procedures
You will not qualify if you...
- Currently using antidepressant, anti-anxiety, or sleep medications including melatonin
- Are pregnant
- Have allergies or sensitivities to scented lotion
- Are unwilling to keep a consistent bedtime (within ±1 hour) during treatment weeks
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Redlands
Redlands, California, United States, 92374
Actively Recruiting
Research Team
L
Lisa E Olson, Ph.D.
CONTACT
S
Steven Moore, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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