Actively Recruiting
The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)
Led by MeMed Diagnostics Ltd. · Updated on 2026-01-21
1316
Participants Needed
10
Research Sites
160 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a Prospective, multi-center study enrolling adults subjects presented to the ED/Urgent care, with symptoms consistent with lower respiratory infection (LRTI). The reason of this study is to demonstrate the MeMed BV can help clinicians make decisions about using antibiotics in patients with lower respiratory track infections and see how it would impact clinical outcomes, antibiotics use, hospitalizations, ED clinicians find ways to improve health and medical care.
CONDITIONS
Official Title
The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Written informed consent must be obtained from the patient or legal guardian.
- Age 18 years or older.
- Current illness lasting 7 days or less.
- Fever of 37.86C (1006F) or higher, or feeling feverish, recorded at least once in the past 7 days.
- Clinical suspicion of bacterial or viral lower respiratory tract infection with symptoms like new or worsening cough, sputum production, shortness of breath, or abnormal lung sounds.
- Clinician plans to prescribe antibiotics based on available data.
You will not qualify if you...
- Use of systemic antibiotics within 72 hours before enrollment.
- Having inflammatory diseases such as IBD, SLE, rheumatoid arthritis, Kawasaki disease, or other vasculitis.
- Having congenital immune deficiency.
- Known or suspected infections with mycobacterial, parasitic, or fungal pathogens.
- Known HIV, HBV, or HCV infection.
- Major surgery, trauma, or burns within the last 7 days.
- Pregnancy (self-reported or medically confirmed).
- Active cancer diagnosed or treated within the past six months or hematological cancer not in remission.
- Severe illnesses affecting life expectancy or quality of life like end-stage kidney or liver disease or severe COPD.
- Clinician intends to hospitalize the patient.
- Suspected other infections like urinary tract infection, cellulitis, or gastroenteritis.
- Current treatment with immune-suppressive or immune-modulating therapies including high-dose steroids, monoclonal antibodies, IVIG, cyclosporine, cyclophosphamide, tacrolimus, azathioprine, methotrexate, or interferons.
- Considered unsuitable for the study by the study team.
AI-Screening
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Trial Site Locations
Total: 10 locations
1
University of Florida-Jacksonville
Jacksonville, Florida, United States, 32209
Actively Recruiting
2
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160
Actively Recruiting
3
Maimonides Medical Center
Brooklyn, New York, United States, 11219
Actively Recruiting
4
Stony Brook University Hospital
Stony Brook, New York, United States, 11794
Actively Recruiting
5
Philadelphia Thomas Jefferson ED
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
6
Medical University South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
7
UT Southwestern Medical Center
Dallas, Texas, United States, 75390
Actively Recruiting
8
MCW
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
9
Carmel Medical Center
Haifa, North, Israel
Actively Recruiting
10
Lin Medical Center
Haifa, Israel
Not Yet Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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