Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
Healthy Volunteers
ID06679491

Effects of Menstrual Cycle-based Undulating Periodized Resistance Training in Women's Neuromuscular Abilities

Led by Universite de La Reunion · Updated on 2024-11-07

60

Participants Needed

1

Research Sites

130 weeks

Total Duration

On this page

Sponsors

U

Universite de La Reunion

Lead Sponsor

P

Physio Formation

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating how resistance training adjusted to menstrual cycle phases affects neuromuscular function in female athletes. The study focuses on whether training intensity changes aligned with menstrual phases improve maximal knee extensor strength and other neuromuscular measures like voluntary activation, rate of force development, muscle stiffness, and vertical jump height. The trial compares female athletes with natural menstrual cycles to those using oral contraceptives to understand hormonal influences on training adaptations. Participants are assigned to one of four groups: three with natural menstrual cycles receiving different resistance training intensities either intensified during the follicular phase, luteal phase, or continuous training across all phases, and a control group of oral contraceptive users undergoing continuous intensity training. Each group completes a 13-week resistance training program with two 90-minute sessions per week, with intensity modulated according to the menstrual cycle phase or contraceptive use. Throughout the study, participants undergo neuromuscular evaluations before and after the training period across the early follicular, late follicular, and mid-luteal phases. Assessments include maximal knee extensor strength, muscle activation, rate of force development, muscle stiffness, and vertical jump height. Blood samples verify hormone levels during testing. The study aims to provide insights for optimizing training based on menstrual phases to improve performance and neuromuscular health in female athletes.

CONDITIONS

Brief Title

Impact of Menstrual Cycle-Based Resistance Training on Neuromuscular Performance in Female Athletes

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Female athletes with natural menstrual cycles lasting 21 to 35 days and at least 9 cycles per year
  • Women using a low-dose monophasic estrogen-progestin oral contraceptive
  • Age 18 years or older
  • Body Mass Index between 18 and 30 kg/m²
  • No medical contraindications to high-level physical training or exercise
  • Physically active with at least 3 hours of physical activity per week
  • Provides written informed consent to participate
  • Affiliated with a social security system (if applicable)
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Resistance Training Program

Duration - 13 weeks

Participants complete a 13-week structured resistance training program tailored to their group, involving two 90-minute sessions per week. Training intensity varies by group and menstrual cycle phase, including intensified training during the follicular phase, luteal phase, or continuous intensity throughout the cycle.

Two training sessions per week

Neuromuscular Assessments

Duration - Assessments occur pre- and post-intervention over the course of the study

Participants undergo neuromuscular testing and blood sampling for hormonal verification before and after the training program during three menstrual phases: early follicular, late follicular, and mid-luteal. These assessments measure muscle strength, activation, stiffness, and jump performance.

6 assessment visits (3 pre-intervention and 3 post-intervention)

Trial Site Locations

Total: 1 location

1

Laboratoire IRISSE (Université de La Réunion)

Le Tampon, France, Reunion, 97430

Actively Recruiting

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Research Team

M

Manon DAUVERGNE, PhD student

J

Josué GAN, Msc.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

4

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