Actively Recruiting

Phase Not Applicable
Age: 21Years +
All Genders
Healthy Volunteers
NCT05555069

The Impact of Menthol Flavoring on Switching in Adult Menthol Smokers

Led by Nikki Nollen, PhD, MA · Updated on 2026-01-23

800

Participants Needed

1

Research Sites

229 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will compare the efficacy of menthol-flavored versus tobacco-flavored 4th generation nicotine salt-based pod-system e-cigarettes in facilitating a switch from combustible cigarettes to e-cigarettes in adult menthol smokers.

CONDITIONS

Official Title

The Impact of Menthol Flavoring on Switching in Adult Menthol Smokers

Who Can Participate

Age: 21Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 21 years or older
  • Smoke 5 or more cigarettes per day
  • Have smoked menthol cigarettes for at least 6 months
  • Verified smoker with carbon monoxide level greater than 5 ppm
  • Have a functioning telephone
  • Interested in switching to e-cigarettes
Not Eligible

You will not qualify if you...

  • Interested in quitting smoking
  • Use of other tobacco products in the past 30 days (e.g., cigarillos, cigars, hookah, smokeless tobacco, pipes)
  • Used e-cigarettes on 4 or more days in the past 30 days
  • Uncontrolled hypertension with blood pressure 180 systolic or higher, or 105 diastolic or higher
  • Use of smoking cessation medications in the month before enrollment
  • Pregnant, planning to become pregnant, or breastfeeding
  • Planning to move from Kansas City during the study period
  • Another household member already enrolled in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Kansas Medical Center

Kansas City, Missouri, United States, 64130

Actively Recruiting

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Research Team

T

Tricia Snow

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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