Actively Recruiting
The Impact of Metabolic Status on Pain and Central Sensitization in Women With Lipedema: A Cross-Sectional Observational Study
Led by Marmara University · Updated on 2026-03-12
59
Participants Needed
1
Research Sites
51 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to evaluate the effect of metabolic markers (HOMA-IR, triglyceride/HDL ratio, HbA1c, waist and hip circumference measurements, BMI, etc.) on pain and central sensitization in patients diagnosed with lipedema. The primary objective is to investigate the association between metabolic markers and central sensitization. The secondary objective is to assess the relationship between metabolic markers and pain intensity, pain phenotype, and functional status.
CONDITIONS
Official Title
The Impact of Metabolic Status on Pain and Central Sensitization in Women With Lipedema: A Cross-Sectional Observational Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Being female and aged 18 years or older
- Having chronic pain persisting for at least 3 months
- Having sufficient cognitive ability to understand and respond to the assessment scales used in the study
- Voluntarily agreeing to participate in the study and providing written informed consent
You will not qualify if you...
- Presence of a history of malignancy, active infection, inflammatory rheumatic disease, or severe systemic disease
- History of known neurological disorders (e.g., stroke, multiple sclerosis, epilepsy)
- Diagnosis of severe psychiatric disorders (e.g., psychotic disorders, bipolar disorder)
- Pregnancy or breastfeeding
- Presence of cognitive impairment or communication difficulties that could affect the study results
- Diagnosed diabetes mellitus
- Active thyroid disease (uncontrolled hypothyroidism or hyperthyroidism)
- Cushing's syndrome or other significant endocrine disorders
- Use of antidiabetic medications
- Use of lipid-lowering therapy (e.g., statins, fibrates)
- Systemic glucocorticoid use within the past 3 months
- Use of medications that may significantly affect central pain mechanisms (e.g., high-dose opioids, antipsychotic drugs)
- History of major surgery or invasive treatment for pain within the past 3 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Marmara University Faculty of Medicine Pendik Training and Research Hospital
Istanbul, Pendik, Turkey (Türkiye), 34890
Actively Recruiting
Research Team
F
Fatma B Akdağ
CONTACT
Y
Yeliz Özdemir
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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