Actively Recruiting

Age: 18Years - 70Years
All Genders
NCT04736381

Impact of the Microbiota on the Likelihood of Renal Graft Rejection

Led by Institut National de la Santé Et de la Recherche Médicale, France · Updated on 2025-04-10

70

Participants Needed

9

Research Sites

274 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Identification of a bacterial signature in the blood or stool that may be associated with acute rejection in patients treated with Nulojix during their first year of transplant.

CONDITIONS

Official Title

Impact of the Microbiota on the Likelihood of Renal Graft Rejection

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients called for a kidney transplant
  • Induction therapy with Simulect, maintenance therapy with Nulojix, mycophenolate acid and steroids
  • Patient having signed the informed consent
Not Eligible

You will not qualify if you...

  • Multiple grafts combined or sequential
  • Induction therapy with polyclonal antibodies
  • HIV or active viral infection such as hepatitis B or C
  • Active bacterial infection
  • Pregnancy or breastfeeding at time of inclusion
  • Patient unable to express their consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 9 locations

1

Nephrologie transplantation CHRU Besançon

Besançon, France, 25000

Actively Recruiting

2

Néphrologie, hémodialyse, aphérèses, transplantation rénale

La Tronche, France, 38700

Actively Recruiting

3

Nephrologie transplantation CHRU Nantes

Nantes, France, 44200

Actively Recruiting

4

Nephrologie transplantation CHU Saint Louis Paris

Paris, France, 75010

Actively Recruiting

5

Nephrologie transplantation CHU Pitié Salpetriere Paris

Paris, France, 75013

Actively Recruiting

6

Nephrologie hôpital Henri-Mondor

Paris, France, 94010 Créteil

Actively Recruiting

7

Nephrologie transplantation CHRU Poitiers

Poitiers, France, 86021

Actively Recruiting

8

Nephrologie transplantation CHRU Toulouse

Toulouse, France, 31059 Toulouse Cedex 9

Actively Recruiting

9

Nephrologie transplantation CHRU Tours

Tours, France, 37044

Actively Recruiting

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Research Team

A

Antoine Durrbach, MD-PhD

CONTACT

F

florence Herr, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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