Actively Recruiting
Impact of Milk and Yogurt Supplementation on Bone Health, Body Composition, and Gut Microbiota in Canadian Young Adults
Led by University of Saskatchewan · Updated on 2024-08-16
99
Participants Needed
1
Research Sites
193 weeks
Total Duration
On this page
Sponsors
U
University of Saskatchewan
Lead Sponsor
D
Dairy Farmers of Canada
Collaborating Sponsor
AI-Summary
What this Trial Is About
Milk and dairy products contain significant amounts of nutrients that contribute to optimal health - nutrients like calcium, vitamin D, and high-quality protein. Fermented milk products or fermented dairy products are dairy foods that have been fermented with certain bacteria. Yogurt is a fermented dairy product containing millions of beneficial bacteria. In this study, the invesgitagtors will look at the effect of milk (a non-fermented dairy product) and yogurt (a fermented dairy product) supplementation on bone health and the amount of fat and muscle mass in Canadian young adults over a 24-month period. While dairy products contain significant amounts of nutrients, the scientific community does not know the impact of long-term supplementation of fermented (i.e., yogurt) or non-fermented (i.e., milk) dairy food on bone health and the amount of fat and muscle mass in young adults. To fill this knowledge gap, the investigators will recruit participants with low calcium intake and assign them to three different groups: 1) milk (intervention) group; 2) yogurt (intervention) group; and 3) control group. The investigators will ask the participants in the milk group to drink 1.5 servings (375 mL) of milk per day for 24 months. Participants in the yogurt group will consume 2 servings (350 g) of yogurt per day for 24 months. Those in the control group will continue their usual diets. Using a randomized controlled trial design, the investigators will measure bone health parameters, hormonal indices related to bone metabolism, body composition (e.g., muscle mass, fat mass), and the number and composition of bacteria living in the gastrointestinal (GI) tract. The hypothesis is that supplementation with yogurt will have more positive effects on bone health indices, particularly femoral neck BMD as the primary outcome, than milk in Canadian adults aged 19-30 years. The secondary hypothesis is that supplementation with yogurt, as a fermented milk product, will have a more beneficial effect than milk on body composition measures. The data will provide valuable information for developing targeted health initiatives and marketing strategies regarding the benefits of fermented and non-fermented dairy product consumption.
CONDITIONS
Official Title
Impact of Milk and Yogurt Supplementation on Bone Health, Body Composition, and Gut Microbiota in Canadian Young Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 19 and 30 years
- Dietary calcium intake below 1000 mg per day
- Living in the Saskatoon area, Saskatchewan, Canada
You will not qualify if you...
- Calcium intake from food and supplements above 800 mg per day
- Total dairy intake of more than 1 serving per day
- Body mass index greater than 30 kg/m2
- Medical history of metabolic bone, liver, endocrine, connective tissue, or respiratory diseases, thyroid disorders, or cancer
- Diagnosed secondary osteoporosis due to hypoparathyroidism
- Hormonal disorders or disturbances
- Taking medications that affect bone mass and density (e.g., steroids, diuretics, heparin, cancer drugs)
- Cow's milk allergy
- Pregnant or lactating women, or planning to become pregnant during the trial
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Saskatchewan
Saskatoon, Saskatchewan, Canada, S7N 5E5
Actively Recruiting
Research Team
H
Hassan Vatanparast, MD, PhD
CONTACT
Z
Zoe Longworth, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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