Actively Recruiting
Impact of Moderate Preterm Birth on Vocabulary Acquisition
Led by Assistance Publique Hopitaux De Marseille · Updated on 2026-01-08
160
Participants Needed
1
Research Sites
417 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Children born prematurely may present a neurodevelopmental disorder with a language delay diagnosed as early as 2-3 years of age. This situation is not uncommon: each year in France, approximately 35,000 children are born between 32 and 36 weeks of amenorrhea. In our most recent work, we have shown that moderate premature infants show an attenuated cortical response to a vowel change, suggesting a deficit in the cortical encoding of vowels. This work needs to be continued in order to better understand syllable encoding and identify the neuroplasticity mechanisms underlying early speech encoding. The identification of markers to predict language development is essential for the screening of these children at risk of language delay. These children could thus benefit from early adapted care even before the appearance of language deficits.
CONDITIONS
Official Title
Impact of Moderate Preterm Birth on Vocabulary Acquisition
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Infants born prematurely (32-36 weeks gestational age) or at term (38-42 weeks gestational age)
- Birth weight appropriate for gestational age based on WHO growth charts
- Normal clinical examination at the time of inclusion
- Written informed consent obtained from both parents or single parent
- Infant has at least one parent who speaks and understands fluent French
- Infant is affiliated with the social security system
- Infant's parents reside in Marseille
You will not qualify if you...
- Neonatal distress with Apgar score less than 7
- Hypoxic and ischemic encephalopathy
- Perinatal acidosis
- Intrauterine growth retardation
- Brain injuries such as intraventricular or periventricular hemorrhage or leukomalacia
- Cerebral congenital malformations
- Neonatal epilepsy
- Any condition considered by the investigator as incompatible with the study
- Abnormal hearing test from routine newborn care
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Service de Neuropédiatrie
Marseille, France, 13005
Actively Recruiting
Research Team
B
Beatrice Desnous, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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