Actively Recruiting
Impact of Muscle Degeneration in Chronic Low Back Pain
Led by Hospital Israelita Albert Einstein · Updated on 2025-03-13
168
Participants Needed
1
Research Sites
272 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Surgical interventions for the removal of intervertebral disc fragments or to enlarge a narrow spine canal are commonly performed worldwide and are considered efficient. Concomitant low back pain is not uncommon among patients with lumbar nerve compression and neurological symptoms. When present, controversy persists in the literature regarding its ideal management. Although neurological symptoms improve after decompressive surgery, the presence of residual chronic low back pain may worsen satisfaction scores and cause functional disability. The hypothesis of the present study is that the presence of atrophy of the paraspinal and trunk muscles predicts chronic low back pain after lumbar neural decompression. If confirmed, this finding will aid in better planning of physical rehabilitation strategies for this group of patients, as well as a clearer prediction regarding surgical treatment outcomes for patients and health professionals.
CONDITIONS
Official Title
Impact of Muscle Degeneration in Chronic Low Back Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years of age and older
- Symptoms of lumbosacral neural compression (radiculopathy or neurogenic claudication)
- Failed conservative treatment for at least 6 weeks
- Undergoing surgery for neural decompression (discectomy, foraminotomy, or hemilaminectomy)
- Complete preoperative and postoperative medical records available for all evaluations
You will not qualify if you...
- Need for lumbar arthrodesis
- Deep infection requiring surgical cleaning
- Prior joint facet rhizotomy
- Active rheumatologic disease, including seronegative arthropathies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital Israelita Albert Einstein
São Paulo, São Paulo, Brazil, 05601-901
Actively Recruiting
Research Team
A
Alberto Gotfryd, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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