Actively Recruiting
The Impact of Music Medicine on Preterm Brain Development and Behavior
Led by Brigham and Women's Hospital · Updated on 2026-03-25
243
Participants Needed
2
Research Sites
301 weeks
Total Duration
On this page
Sponsors
B
Brigham and Women's Hospital
Lead Sponsor
Y
Yale New Haven Health System Center for Healthcare Solutions
Collaborating Sponsor
AI-Summary
What this Trial Is About
The investigators are conducting a two-site randomized control trial with the aim of defining the impact of music (M) without or with parent voice (MPV) on very preterm infants' acute and cumulative stress, intranetwork connectivity on term brain MRI, and language and other neurodevelopmental outcomes at two years corrected age. This is based on the hypothesis that infants in MPV arm are expected to experience the greatest benefit compared with infants receiving standard care.
CONDITIONS
Official Title
The Impact of Music Medicine on Preterm Brain Development and Behavior
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Very preterm infants born between 24+0 and 30+6 weeks gestational age
- Infants who are medically stable as determined by the clinical care team
- Infants from two level III NICUs (Brigham and Women's Hospital, Boston, MA and Yale New Haven, CT)
You will not qualify if you...
- Infants with major genetic or congenital anomalies known to cause developmental delay
- Infants with severe brain injury such as intraparenchymal hemorrhage or severe white matter injury
- Infants who are severely ill and for whom music-based intervention is not feasible
- Infants of parents unable to complete questionnaires in English or Spanish
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Yale New Haven Hospital
New Haven, Connecticut, United States, 06510
Not Yet Recruiting
2
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
C
Carmina Erdei, MD
CONTACT
I
Isabella J Lawandy
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here