A survey of postoperative nausea and vomiting.
M Koivuranta, E Läärä, L Snåre...
https://pubmed.ncbi.nlm.nih.gov/9165963Actively Recruiting
Phase Not Applicable
Age: 16Years +
All Genders
Healthy Volunteers
ID06422793
The Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting in Orthognathic Surgery
Led by Nova Scotia Health Authority · Updated on 2025-01-14
92
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to compare the occurrence of nausea and vomiting within the first 24 hours after corrective jaw surgery, known as orthognathic surgery. It focuses on patients undergoing this surgery and evaluates how using a nasogastric (NG) tube for stomach decompression during and shortly after surgery may affect these symptoms. The study also considers other factors such as anesthesia type, surgery length, surgery type, and patient characteristics that might influence nausea and vomiting. Participants will be randomly assigned to one of two groups. One group will not have an NG tube inserted during surgery, while the other group will receive NG tube gastric decompression following a specific protocol. For the decompression group, a tube will be inserted after anesthesia and connected to suction to remove stomach contents during surgery and for one hour after surgery. The tube will then be removed. Both groups will otherwise receive the same surgical care. During the study, participants will be monitored for nausea and vomiting at two time points: early (0 to 2 hours after surgery) and delayed (2 to 24 hours after surgery). Researchers will document any complications related to the NG tube and assess various factors that might impact nausea and vomiting. The study will use patient assessments and surgical records to measure outcomes, with participation lasting through the immediate 24-hour postoperative period.
CONDITIONS
Brief Title
The Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting in Orthognathic Surgery
Who Can Participate
Age: 16Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Patients over the age of 16 at the time of consent undergoing orthognathic surgery for correction of dentofacial deformities during the study period.
- Patients receiving single-jaw surgery (Bilateral Sagittal Split Osteotomy only or LeFort only).
- Patients receiving double-jaw surgery (Bilateral Sagittal Split Osteotomy and LeFort).
- Patients undergoing a functional genioplasty in addition to another osteotomy (Bilateral Sagittal Split Osteotomy and/or LeFort).
You will not qualify if you...
- Patients under the age of 16 at the time of consent.
- Patients contraindicated to undergo elective surgery, including pregnant patients.
- Patients undergoing a functional genioplasty procedure only.
- Patients taking GLP-1 receptor agonists.
- Patients with known gastroparesis.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - Surgery day and 1 hour postoperatively
Participants undergo orthognathic surgery with or without nasogastric tube gastric decompression during surgery and up to one hour postoperatively.
1 surgical visit and 1 immediate post-operative observation
Post-operative Follow-up
Duration - 24 hours postoperatively
Participants are monitored for early and delayed postoperative nausea and vomiting up to 24 hours after surgery.
2 assessments (0-2 hours and 2-24 hours postoperatively)
Trial Site Locations
Total: 1 location
1
Victoria General Hospital
Halifax, Nova Scotia, Canada, B3H 2Y9
Actively Recruiting
Loading map...
Research Team
K
Katherine A Curry, DDS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Nausea, vomiting, and hiccups: a review of mechanisms and treatment.
Daniel E Becker
https://pubmed.ncbi.nlm.nih.gov/21174569Incidence and risk factors for postoperative nausea and vomiting in orthognathic surgery: a 10-year retrospective study.
Subhabrata Ghosh, Kirthi Kumar Rai, Hosadurga Rudraswamy Shivakumar...
https://pubmed.ncbi.nlm.nih.gov/32364351Unanticipated admission after ambulatory surgery--a prospective study.
J Fortier, F Chung, J Su
https://pubmed.ncbi.nlm.nih.gov/9717590Prevention and treatment of postoperative nausea and vomiting.
A L Kovac
https://pubmed.ncbi.nlm.nih.gov/10730546Postoperative nausea and vomiting after general anesthesia for oral and maxillofacial surgery.
Benjamas Apipan, Duangdee Rummasak, Natthamet Wongsirichat
https://pubmed.ncbi.nlm.nih.gov/28879315Mechanisms of Nausea and Vomiting: Current Knowledge and Recent Advances in Intracellular Emetic Signaling Systems.
Weixia Zhong, Omar Shahbaz, Garrett Teskey...
https://pubmed.ncbi.nlm.nih.gov/34071460Postoperative nausea and vomiting after oral and maxillofacial surgery: a prospective study.
M Dobbeleir, J De Coster, W Coucke...
https://pubmed.ncbi.nlm.nih.gov/29301675Postoperative nausea and vomiting (PONV) after orthognathic surgery: a retrospective study and literature review.
Alessandro C Silva, Felice O'Ryan, David B Poor
https://pubmed.ncbi.nlm.nih.gov/16916674Risk assessment of postoperative nausea and vomiting.
Christian C Apfel, Norbert Roewer
https://pubmed.ncbi.nlm.nih.gov/14574212