A survey of postoperative nausea and vomiting.
M Koivuranta, E Läärä, L Snåre...
https://pubmed.ncbi.nlm.nih.gov/9165963Actively Recruiting
Phase Not Applicable
Age: 16Years +
All Genders
Healthy Volunteers
ID06422793
Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting During Orthognathic Surgery
Led by Nova Scotia Health Authority · Updated on 2025-01-14
92
Participants Needed
1
Research Sites
51 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effect of nasogastric tube gastric decompression on the occurrence of postoperative nausea and vomiting (PONV) in patients undergoing corrective jaw surgery, known as orthognathic surgery. PONV affects up to 60% of these patients and is believed to be mainly caused by gastric pooling of blood after surgery. This study compares the incidence of PONV in patients with and without the use of nasogastric (NG) tube gastric decompression during the first 24 hours after surgery. Other factors such as anesthesia type, surgery length, surgery type, and patient characteristics will also be examined for their impact on PONV. Participants will be randomly assigned to one of two groups: one group will receive NG tube gastric decompression during surgery with the tube removed one hour after surgery, and the other group will not receive NG tube gastric decompression. Orthognathic surgeries included in this study are single-jaw surgeries like Bilateral Sagittal Split Osteotomy (BSSO) or LeFort osteotomy, double-jaw surgeries involving both BSSO and LeFort, and surgeries including a functional genioplasty combined with other osteotomies. The study is conducted at Victoria General Hospital. During the study, participants will be monitored for early PONV within the first 2 hours after surgery and delayed PONV from 2 to 24 hours postoperatively. Researchers will collect data on the presence and severity of nausea and vomiting to assess the impact of NG tube gastric decompression. The study also tracks other relevant variables to better understand their role in PONV. Participant involvement includes surgery, possible NG tube placement, and monitoring for up to 24 hours after surgery.
CONDITIONS
Official Title
The Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting in Orthognathic Surgery
Who Can Participate
Age: 16Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Patients 16 years or older at time of consent undergoing orthognathic surgery for dentofacial deformities at Victoria General Hospital
- Patients receiving single-jaw surgery (Bilateral Sagittal Split Osteotomy only, or LeFort only)
- Patients receiving double-jaw surgery (Bilateral Sagittal Split Osteotomy and LeFort)
- Patients undergoing a functional genioplasty combined with another osteotomy (Bilateral Sagittal Split Osteotomy and/or LeFort)
You will not qualify if you...
- Patients under 16 years old at time of consent
- Patients contraindicated for elective surgery, including pregnant patients
- Patients undergoing only a functional genioplasty procedure
- Patients taking GLP-1 receptor agonists
- Patients with known gastroparesis
AI-Screening
AI-Powered Screening
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1
2
3
Trial Site Locations
Total: 1 location
1
Victoria General Hospital
Halifax, Nova Scotia, Canada, B3H 2Y9
Actively Recruiting
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Research Team
K
Katherine A Curry, DDS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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Published Research Related To This Trial
Nausea, vomiting, and hiccups: a review of mechanisms and treatment.
Daniel E Becker
https://pubmed.ncbi.nlm.nih.gov/21174569Incidence and risk factors for postoperative nausea and vomiting in orthognathic surgery: a 10-year retrospective study.
Subhabrata Ghosh, Kirthi Kumar Rai, Hosadurga Rudraswamy Shivakumar...
https://pubmed.ncbi.nlm.nih.gov/32364351Unanticipated admission after ambulatory surgery--a prospective study.
J Fortier, F Chung, J Su
https://pubmed.ncbi.nlm.nih.gov/9717590Prevention and treatment of postoperative nausea and vomiting.
A L Kovac
https://pubmed.ncbi.nlm.nih.gov/10730546Postoperative nausea and vomiting after general anesthesia for oral and maxillofacial surgery.
Benjamas Apipan, Duangdee Rummasak, Natthamet Wongsirichat
https://pubmed.ncbi.nlm.nih.gov/28879315Mechanisms of Nausea and Vomiting: Current Knowledge and Recent Advances in Intracellular Emetic Signaling Systems.
Weixia Zhong, Omar Shahbaz, Garrett Teskey...
https://pubmed.ncbi.nlm.nih.gov/34071460Postoperative nausea and vomiting after oral and maxillofacial surgery: a prospective study.
M Dobbeleir, J De Coster, W Coucke...
https://pubmed.ncbi.nlm.nih.gov/29301675Postoperative nausea and vomiting (PONV) after orthognathic surgery: a retrospective study and literature review.
Alessandro C Silva, Felice O'Ryan, David B Poor
https://pubmed.ncbi.nlm.nih.gov/16916674Risk assessment of postoperative nausea and vomiting.
Christian C Apfel, Norbert Roewer
https://pubmed.ncbi.nlm.nih.gov/14574212