Effect of Neuromuscular Electrical Stimulation and High Protein Supplements on Recovery After Aneurysmal Subarachnoid Hemorrhage in Adults

What this Trial Is About

Researchers are evaluating whether early neuromuscular electrical stimulation NMES combined with high protein supplementation HPRO can improve muscle mass, metabolic, and inflammatory markers in adults who have experienced aneurysmal subarachnoid hemorrhage SAH. This study compares patients receiving NMES and HPRO against those receiving standard nutritional and mobilization care. It aims to understand how these interventions may reduce muscle wasting and improve recovery by addressing inflammation and energy balance after SAH. Participants are assigned to one of four groups standard care, NMES only, HPRO only, or both NMES and HPRO. NMES involves two 30-minute sessions daily, while HPRO is given three times daily, including immediately after NMES and at night. All patients receive standard mobilization and nutrition support throughout the study period. Participants will be closely monitored over a 14-day period with muscle thickness of the quadriceps measured by ultrasound to assess changes. Researchers will also collect data on inflammatory and metabolic biomarkers. The study includes regular assessments and aims to track muscle and health recovery outcomes following SAH, under the sponsorship of the University of Maryland, Baltimore.

Impact of NMES and HPRO on Recovery After SAH- Pilot Study