Actively Recruiting
The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
Led by Massachusetts General Hospital · Updated on 2025-05-08
30
Participants Needed
1
Research Sites
216 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to determine whether modifying the timing of nutrition support from overnight to daytime enhances sleep quality, preserves circadian rhythms, and improves overall inflammation and cardiometabolic profiles in postoperative patients in the cardiac surgical ICU on enteral nutrition.
CONDITIONS
Official Title
The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult male or non-pregnant female volunteers aged 18 years or older
- Scheduled for cardiac surgery with planned post-operative ICU admission longer than 48 hours
- Able and willing to give consent and comply with study procedures
You will not qualify if you...
- Blind, deaf, or unable to speak English
- Pregnant or nursing women
- Contraindications to safe use of enteral nutrition, including gastrointestinal obstruction
- Personal history of intestinal malabsorption, gallbladder disease, or pancreatitis
- Dietary restrictions precluding enteral feeds
- Renal or liver failure requiring dialysis or Child-Pugh score greater than 7
- Severe brain damage from structural or anoxic causes
- Skin conditions preventing use of sensors
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
H
Hassan S Dashti, Ph.D., R.D.
CONTACT
R
Richa Saxena, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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