Actively Recruiting
IMPACT 360 for Parkinson's Disease
Led by University of British Columbia · Updated on 2026-03-02
60
Participants Needed
1
Research Sites
165 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The IMPACT 360 study will evaluate the effects of a combined intervention of exercise, mindfulness, and nutrition on 8 key indicators of health and the mechanisms that drive these changes. 60 subjects aged 40 to 85 with a current diagnosis Parkinson's disease will be recruited. This study will follow a partial crossover design. All participants will receive the intervention. Participants randomized into the intervention group after their baseline screening will receive the 6-month intervention. Those randomized into the waitlist group will complete another assessment at the end of the 6-month care as usual phase before receiving the intervention.
CONDITIONS
Official Title
IMPACT 360 for Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 40 to 85 years
- Diagnosis of Parkinson's disease based on Movement Disorder Society criteria or REM Sleep Behavior Disorder via polysomnography
- Hoehn & Yahr score between 1 and 2
- Ability to complete questionnaires
- Ability to follow instructions and directions required by the intervention
- Access to necessary technology such as a smartphone for Fitbit and a laptop or tablet for Zoom
You will not qualify if you...
- Any chronic medical condition limiting ability to participate in exercise
- Contraindications for exercise based on PAR-Q+ and medical clearance
- Significant cognitive impairment, depression, or eating disorder
- Montreal Cognitive Assessment score below 21 out of 30
- Contraindications to MRI scanning including implanted metal devices or fragments
- Medical advice requiring supervised exercise
- Currently doing 180 minutes or more of moderate-vigorous exercise weekly and completed Mindfulness-Based Stress Reduction course or high score on MIND Diet Questionnaire
- Significant or unstable cardiovascular or respiratory disease
- Severe or multiple head trauma
- Pregnancy or breastfeeding
- History of major drug or alcohol abuse
- Chronic or acute bacterial or viral infection
- Gastrointestinal cancer or inflammatory bowel disease
- Weight over 400 pounds
- Presence of artificial heart valve, brain aneurysm clip, electrical nerve or bone stimulator, ear or eye implant, drug infusion pump, blood vessel coil or filter, orthopedic hardware, shrapnel, bullets, or other metal fragments
- Recent surgery or tattoos within six weeks
- Brain surgery
- Cardiac pacemaker, wires, or defibrillator
- Metal lodged in eye or orbit
- Ferromagnetic aneurysm clip
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of British Colombia
Vancouver, British Columbia, Canada, V6T 1Z3
Actively Recruiting
Research Team
J
Jeffrey Kelly
CONTACT
A
Annie Kuan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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