Actively Recruiting

Age: 18Years +
All Genders
NCT06907758

Impact of Perioperative Organ Resuscitation of Brain-dead Deceased Organ Donor on Kidney Graft Function in the Recipient

Led by University Hospital, Strasbourg, France · Updated on 2025-04-02

50

Participants Needed

1

Research Sites

87 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Brain-dead patients are the primary source of grafts for those awaiting organ transplantation. Recommendations exist for the management of these potential donors, based on the concept of organ resuscitation, according to which targeted resuscitation would improve graft quality and quantity. Graft performance thus depends on fixed factors (donor/recipient age, medical history, etc.) but also potentially modifiable factors. Through this study, the investigators aim to identify potentially modifiable factors in our donor care (in intensive care and the operating room) that may influence graft function in the recipient. For simplicity, the investigators will focus on kidney grafts. The aim is to improve the effectiveness of the transplant and reduce waiting times.

CONDITIONS

Official Title

Impact of Perioperative Organ Resuscitation of Brain-dead Deceased Organ Donor on Kidney Graft Function in the Recipient

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patient
  • Brain dead
  • Hospitalized in surgical intensive care at Strasbourg University Hospital from January 1, 2018 to December 31, 2023
  • Underwent multi-organ transplantation
  • At least one donor kidney transplanted to a patient at Strasbourg University Hospital
  • No written objection in medical records to data reuse for research
  • Adult kidney transplant recipient of a kidney from a donor meeting the above criteria
  • Recipient patient operated on and hospitalized post-operatively at Strasbourg University Hospital
  • Monitored by Strasbourg University Hospital transplant team
  • No written objection in medical records to data reuse for research
Not Eligible

You will not qualify if you...

  • Expressed opposition to reuse of data for scientific research
  • Brain-dead patient without organ retrieval
  • Brain-dead patient whose kidney was not allocated to Strasbourg recipient
  • Patient transferred to Strasbourg ICU from another hospital solely for organ retrieval after brain death diagnosis
  • Kidney transplant patient with graft from living donor
  • Kidney transplant patient with graft from deceased donor who is not brain-dead
  • Kidney transplant patient with graft from brain-dead donor hospitalized outside Strasbourg

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Service d'Anesthésie, Réanimation et Médecine Périopératoire - CHU de Strasbourg - France

Strasbourg, France, 67091

Actively Recruiting

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Research Team

C

Charlotte POUSSARDIN, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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