Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06406218

The Impact of Phase I Cardiac Rehabilitation on the Prognosis of AMI Patients After PCI

Led by Han Yaling, MD · Updated on 2024-05-09

1100

Participants Needed

1

Research Sites

105 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Previous research has confirmed that patients undergoing percutaneous coronary intervention (PCI) can benefit from cardiac rehabilitation programs. However, there is a paucity of studies on Phase I cardiac rehabilitation commenced within three days following PCI in patients with acute myocardial infarction (AMI). Consequently, the objective of the study is to demonstrate whether Phase I cardiac rehabilitation can improve the prognosis at 12 months when compared with the control group. The primary endpoint is the Seattle Angina Questionnaire (SAQ) score at 12 months for the patients. The principal hypothesis of the study is that Phase I cardiac rehabilitation will improve the long-term prognosis for AMI patients at 12 months after PCI.

CONDITIONS

Official Title

The Impact of Phase I Cardiac Rehabilitation on the Prognosis of AMI Patients After PCI

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with acute myocardial infarction (including STEMI and NSTEMI) treated in the coronary care unit for more than 12 hours after emergency PCI
  • Expected to meet discharge criteria without needing repeat PCI during current hospital stay
  • No chest pain episodes within 8 hours and no recurrence of myocardial infarction; hemodynamically stable
  • No further increase in cardiac biomarkers such as CK-MB and cardiac troponins
Not Eligible

You will not qualify if you...

  • Killip class III or higher, or symptoms/signs of acute pulmonary edema and respiratory distress
  • Malignant arrhythmias causing hemodynamic instability or life-threatening conditions
  • Mechanical heart lesions such as ventricular wall rupture or valve/tendon rupture
  • Not yet weaned off ECMO, IABP, temporary pacemakers, or CRRT
  • Liver or kidney dysfunction (transaminase >3 times upper limit or EGFR <30 ml/min/1.73m²) or advanced malignant tumors
  • Unable to perform exercise rehabilitation due to orthopedic or psychiatric diseases
  • Language impairment
  • Currently in systematic training or other clinical trials without primary endpoint collected
  • Considered unsuitable for participation by researchers or lack of informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

General Hospital of Northern Theater Command

Shenyang, Liaoning, China, 110016

Actively Recruiting

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Research Team

Y

Ya-Ling Han, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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