Actively Recruiting
Impact of Pilates Exercises on Bone Mineral Density in Breast Cancer Survivors Receiving Hormonal Therapy
Led by Benha University · Updated on 2026-01-15
60
Participants Needed
1
Research Sites
38 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Breast cancer survivors receiving endocrine (hormonal) therapy (aromatase inhibitors) are at high risk for cancer treatment-induced bone loss and osteoporosis due to estrogen depletion.
CONDITIONS
Official Title
Impact of Pilates Exercises on Bone Mineral Density in Breast Cancer Survivors Receiving Hormonal Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female breast cancer survivors aged 40-60 years
- Histologically confirmed stage I-III breast cancer
- Currently receiving hormonal therapy (aromatase inhibitors) for at least 3 months
- At risk of osteoporosis or with low bone mineral density defined by T-score 64 -1.0 at lumbar spine or hip
- Medically cleared for low-to-moderate intensity Pilates exercise
- Able to attend supervised exercise sessions three times per week for 12 weeks
- Willing and able to provide written informed consent
You will not qualify if you...
- Metastatic (stage IV) or recurrent breast cancer
- History of osteoporotic fractures in the past 12 months
- Severe cardiovascular, respiratory, or musculoskeletal conditions contraindicating exercise
- Uncontrolled hypertension, diabetes, or thyroid disorders
- Current use of corticosteroids
- Active bone metabolic diseases other than osteoporosis (e.g., Paget's disease, osteomalacia)
- Severe cognitive impairment or psychiatric illness preventing adherence
- Known allergy or intolerance to calcium or vitamin D supplementation
- Participation in another clinical trial with structured exercise or bone-targeted intervention within the last 3 months
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Outpatient clinic, faculty of Physical Therapy, Benha university
Banhā, Benha, Egypt, 11603
Actively Recruiting
Research Team
M
Mahmoud Hamada Mohamed Associate Professor, Ph.D
CONTACT
A
Ahmed Mounir Salama Associate Professor, Ph.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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