Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07123857

Impact of Point-of-care Lactate Testing as Triage Supplement on Patient Management Using Manchester Triage System

Led by University Medical Centre Maribor · Updated on 2025-08-14

200

Participants Needed

1

Research Sites

77 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Although the Manchester Triage System (MTS) is widely used and validated internationally, it has some limitations. Its accuracy is moderate, especially for children and the elderly. Rising patient numbers and overcrowded emergency departments increase wait times, sometimes beyond safe limits. In Slovenia, MTS has been in use for 14 years without major updates, despite a significant rise in emergency visits. The yellow triage category (60-minute wait time) includes a very diverse group of patients, some of whom might require faster care. Older patients, in particular, often show atypical symptoms and may be under-triaged. Including rapid bedside lab tests, like blood lactate levels, could improve risk assessment and triage accuracy. Elevated lactate is linked with higher mortality and can help identify critically ill patients more effectively. The proposed study is a prospective, randomized trial involving two groups of patients in the yellow triage category, all of whom will have their capillary blood lactate levels measured. Patients with normal lactate levels will be excluded. Only patients with elevated lactate will be compared. The test group will be re-triaged to the orange category and treated more urgently. The control group, despite also having high lactate levels, will remain in the yellow category, and their elevated lactate values will not be shared with the treating physician. Randomization will be based on the patient's birth date (even days = test group, odd days = control group). Only the nurse will know the result, maintaining physician blinding to avoid the Hawthorne effect-changes in behavior due to awareness of being studied. Standard lab tests will be performed later during treatment as deemed necessary by the attending doctor.

CONDITIONS

Official Title

Impact of Point-of-care Lactate Testing as Triage Supplement on Patient Management Using Manchester Triage System

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed consent to participate
  • Assigned to the yellow category in the Manchester Triage System
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Trauma patients
  • Patients with epileptic seizures
  • Patients receiving adrenergic therapy in prehospital care

AI-Screening

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Trial Site Locations

Total: 1 location

1

University Medical Center Maribor

Maribor, Slovenia

Actively Recruiting

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Research Team

J

Jerica Zaloznik Djordjevic, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SCREENING

Number of Arms

2

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