Actively Recruiting
Impact of Prehabilitation in Oncology Via Exercise- Esophageal (IMPROVE-Esophageal)
Led by University of Pittsburgh · Updated on 2026-01-08
20
Participants Needed
1
Research Sites
63 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to determine the feasibility of a prehabilitation exercise and nutrition program (exercise and nutrition before a medical treatment) in adults with esophageal cancer before surgery (esophagectomy). The pre-surgery exercise and nutrition program will include resistance and aerobic training and nutrition supplementation during the weeks before surgery. We will also assess pre-surgical care needs in adults with esophageal cancer. Researchers will compare the exercise and nutrition intervention to usual care- which is standard medical care and post-surgery surveillance/follow-up to understand the impact of exercise and nutrition before surgery. We will follow-up with participants before surgery, and after surgery at 2 weeks, 6 weeks, and 4-months at appointments that coincide with clinical follow-ups. The main questions of this trials are: * Is exercise and nutrition supplementation before surgery for esophageal cancer feasible and acceptable to patients? * How does exercise and nutrition supplementation before surgery change physical function and psychosocial health? * What are important pre-surgical needs for adults with esophageal cancer?
CONDITIONS
Official Title
Impact of Prehabilitation in Oncology Via Exercise- Esophageal (IMPROVE-Esophageal)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women, age 65 18 years old
- Diagnosed with esophageal cancer
- Identified as esophagectomy surgery candidates at Hillman Cancer Center or UPMC Shadyside
- At least 2 weeks until scheduled esophagectomy
- ECOG Performance Status Scale score of 64 2
- Ability to provide written informed consent
- Ability to understand, speak, and read English
You will not qualify if you...
- Medical record shows absolute contraindication for exercise (e.g., heart insufficiency > NYHA III, uncertain arrhythmia, uncontrolled hypertension, reduced standing or walking ability)
- Other comorbidities or musculoskeletal problems preventing exercise participation as determined by the exercise interventionist
- Receiving chemotherapy or radiotherapy not related to esophagectomy
- Active infections, hemorrhages, or cytopenias that increase surgical risks, as determined by medical staff
AI-Screening
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Trial Site Locations
Total: 1 location
1
UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
Research Team
C
Cara Battistella, MA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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