Actively Recruiting

Age: 18Years +
All Genders
NCT05933876

The Impact of Radiotherapy on Oligometastatic Cancer

Led by Institut Investigacio Sanitaria Pere Virgili · Updated on 2024-11-18

2000

Participants Needed

21

Research Sites

787 weeks

Total Duration

On this page

Sponsors

I

Institut Investigacio Sanitaria Pere Virgili

Lead Sponsor

H

Hospital Ruber Internacional

Collaborating Sponsor

AI-Summary

What this Trial Is About

Metastases represent the most threatening challenge in cancer. One of the management strategies for patients with Oligometastatic Cancer (OC) is Stereotactic ABlative Radiotherapy (SABR). However, there are few studies, and there is no defined clinical standard, nor are the radiobiological mechanisms that contribute to treatment response well understood. The focus should be on generating evidence to guide the personalization of radiotherapy beyond solely technological and anatomical precision. This could be achieved by recollecting clinical and biological data from patients that undergo this treatment and analyzing them to ultimately predict, with the help of artificial intelligence, which patients will be the most beneficiary and improve their survival rate.

CONDITIONS

Official Title

The Impact of Radiotherapy on Oligometastatic Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologic confirmation of primary tumor: breast, prostate, lung, colorectal.
  • 18 years old or older.
  • Up to five metastases located in the bone, lung, node, liver or brain.
  • Eastern Cooperative Oncology Group (ECOG) Performance Status Scale 0 or 1.
Not Eligible

You will not qualify if you...

  • Non-melanoma skin cancer.
  • Previous radiotherapy in the same anatomic location.
  • Presence of vascular collagen disease.
  • Pregnancy or lactation at the time of inclusion.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 21 locations

1

Complejo Hospitalario Universitario Albacete

Albacete, Albacete, Spain

Not Yet Recruiting

2

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Barcelona, Barcelona, Spain

Not Yet Recruiting

3

Hospital Universitari Vall d'Hebron

Barcelona, Barcelona, Spain

Not Yet Recruiting

4

Institut Català d'Oncologia

Barcelona, Barcelona, Spain

Not Yet Recruiting

5

Hospital Universitario Virgen de las Nieves

Granada, Granada, Spain

Not Yet Recruiting

6

Hospital Universitari Arnau de Vilanova

Lleida, Lleida, Spain

Not Yet Recruiting

7

Hospital de La Luz

Madrid, Madrid, Spain

Not Yet Recruiting

8

Hospital Ruber Internacional

Madrid, Madrid, Spain

Not Yet Recruiting

9

Hospital Universitario HM Sanchinarro

Madrid, Madrid, Spain

Not Yet Recruiting

10

Hospital Universitario Quirónsalud

Madrid, Madrid, Spain

Not Yet Recruiting

11

Hospital Universitario Rey Juan Carlos

Madrid, Madrid, Spain

Not Yet Recruiting

12

Hospital Universitario Virgen Macarena

Seville, Sevilla, Spain

Not Yet Recruiting

13

Hospital Universitari Sant Joan de Reus

Reus, Tarragona, Spain, 43204

Actively Recruiting

14

Hospital Clínico Universitario de Valencia

Valencia, Valencia, Spain

Not Yet Recruiting

15

Hospital General Univesitario de Valencia

Valencia, Valencia, Spain

Not Yet Recruiting

16

Hospital Universitari Miguel Servet

Zaragoza, Zaragoza, Spain

Not Yet Recruiting

17

Hospital del Mar

Barcelona, Spain

Not Yet Recruiting

18

Hospital Provincial de Castellón

Castellon, Spain

Not Yet Recruiting

19

Institut Català d'Oncologia

Girona, Spain

Not Yet Recruiting

20

Hospital Universitario Ramón y Cajal

Madrid, Spain

Not Yet Recruiting

21

Hospital de Terrassa

Terrassa, Spain

Not Yet Recruiting

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Research Team

J

Jorge Joven, Prof.

CONTACT

M

Meritxell Arenas, PhD.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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