Actively Recruiting

Age: 18Years +
All Genders
NCT07001189

Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients

Led by Centre Hospitalier Universitaire de la Guadeloupe · Updated on 2025-06-03

34

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Sickle cell disease is a chronic disease characterized by multiple vaso-occlusive complications. The basic treatment for patients with a vaso-occlusive crisis (VOC) is based on adequate hydration, oxygen therapy and pain control. Loco Regional Anesthesia (LRA) is one of the major treatments in resuscitation anesthesia for both anesthesia and analgesia. LRA allows effective and almost immediate pain control by blocking nerve afferents in a given area. LRA could decrease the inflammatory response during crises and accelerate resolution of the crisis.

CONDITIONS

Official Title

Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients older than 18 years
  • Patients currently experiencing a vaso-occlusive crisis
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding women
  • Blood transfusion within the last 3 months
  • Not affiliated with the French social security system
  • Protected individuals

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
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Trial Site Locations

Total: 1 location

1

Chu de La Guadeloupe

Pointe-à-Pitre, Guadeloupe, 97159

Actively Recruiting

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Research Team

V

Valérie Hamony Soter

CONTACT

M

Mélanie Petapermal

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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