Actively Recruiting
The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults
Led by Old Dominion University · Updated on 2024-04-10
40
Participants Needed
1
Research Sites
140 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to determine if an acute bout of removal of exercise reduces enothelial function and glycemic control in an active, older adult population; and whether a 3 day return to exercise restores this response. Glycemic control is the blood glucose response following the consumption of a meal. It is an indicator of insulin resistance (or type 2 diabetes) and impaired glycemic control has been suggested to lead to cardiovascular disease. Endothelial function has been shown to be improved by chronic or acute increases in physical activity. Both of these have been shown to be impaired to acute bouts of inactivity in young populations; however the impact of acute inactivity in older adults is less understood. In this proposal the investigators will examine 1)how quickly impairments in glycemic control occur to acute physical inactivity in older adults who exercise, 2) how quickly impairments in endothelial function occur to acute inactivity in older adults who exercise, and 3) whether 3 days of a return to exercise restores these responses.
CONDITIONS
Official Title
The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be 55 years or older, or between 18 and 40 years old
- Be healthy and physically active, exercising at least 90 minutes per week
- Have no physical limitations that could interfere with changes in daily physical activity levels
You will not qualify if you...
- Have a doctor diagnosis of HIV, hepatitis, or tuberculosis
- Have had a body weight change greater than 5% in the past 2 months
- Have smoked within the past 2 months
- Be taking medications that affect blood glucose levels
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Old Dominion University
Norfolk, Virginia, United States, 23529
Actively Recruiting
Research Team
L
Leryn Reynolds
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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