Actively Recruiting
Impact of Resistance Training Intensity on Blood Pressure
Led by Université de Sherbrooke · Updated on 2025-09-09
36
Participants Needed
1
Research Sites
177 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of the clinical trial is to understand the effect of two resistance training protocols employing different loading intensities (% of 1 repetition maximum; 1-RM), but with standardized effort intensity (2 repetitions in reserve; RIR) on post-exercise and ambulatory blood pressure in aging females. The main questions it aims to answer are: * to examine the acute effects of low (50% 1-RM) and high (80% 1-RM) load intensity resistance exercise with a standardized high effort intensity on post-exercise hypotension and ambulatory blood pressure responses in aging females; * deepen the understanding of the mechanisms underlying acute reductions in blood pressure in response to resistance exercise performed at different load intensities. To this end, autonomic activity will be estimated alongside the measurement of central arterial compliance (i.e., carotid artery), and serum biomarkers of endothelial function; * document the affective valence and enjoyment associated with low (50% 1-RM) and high (80% 1-RM) load intensity resistance exercise when performed at a high perceived effort. Researchers will compare the effect of: 1) a low load (LL-RE) intensity protocol consisting of 3 sets of each exercise at 50% 1-RM, performed until reaching a hard perceived effort intensity (i.e., RIR-2); 2) high load (HL-RE) intensity protocol consisting of 3 sets of each exercise at 80% of 1-RM, performed until reaching a hard perceived effort intensity (i.e., RIR-2); 3) and a control condition (CON) consisting of a standardized non-fatiguing cognitive task. Participants will participate in: * A preliminary assessment visit; * Two familiarization visits to validate the exercise prescriptions; * Three experimental visits (CON, LL-RE, HL-RE).
CONDITIONS
Official Title
Impact of Resistance Training Intensity on Blood Pressure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 50 to 70 years
- No menstruation for at least 12 consecutive months
- Normal-high resting blood pressure (Systolic 120-139 mmHg and Diastolic 80-89 mmHg) or stage 1 hypertension (Systolic 140-159 mmHg or Diastolic 90-99 mmHg)
- Physically inactive, less than 150 minutes of structured aerobic activity per week
- Not regularly doing resistance exercise (2 or more sessions per week) in the past 3 months
You will not qualify if you...
- Orthopedic limitations or contraindications to resistance exercise
- Scheduled surgery during the study period
- Unstable hypertension (blood pressure 160/100 mmHg or higher)
- Diagnosis of type 2 diabetes
- Cardiovascular event in the past 6 months or related exercise limitations
- Started hormonal replacement therapy less than 4 months ago that affects blood pressure
AI-Screening
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Trial Site Locations
Total: 1 location
1
Research Center on Aging
Sherbrooke, Quebec, Canada, J1H 2J7
Actively Recruiting
Research Team
E
Eléonor Riesco, Ph.D.
CONTACT
R
Renaud Tremblay, M.Sc.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
3
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