Actively Recruiting
The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement
Led by Negovsky Reanimatology Research Institute · Updated on 2026-04-15
220
Participants Needed
1
Research Sites
230 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Total knee replacement (TKR) is considered the most effective and safe method of radical treatment of late stages of knee osteoarthritis. A well-known problem of TKR is a severe postoperative pain syndrome, which is observed in more than 50% of patients. Femoral nerve block (FNB) is the "gold standard" for continuous postoperative analgesia after total knee replacement, as it is effective in reducing the frequency of use of opioid analgetics and reduce the duration of hospitalization. At the same time, the negative effect of this method is the motor blockade of the quadriceps femoris muscle which leads to functional impairment and is associated with an increased risk of falling. Adductor canal block (ACB) provides adequate analgesia comparable to femoral nerve block. Moreover, ACB doesn't affect the motor function of the quadriceps femoris muscle. The possibility of enhanced recovery after total knee replacement is the reason to compare single-shot adductor canal block and continuous femoral nerve block.
CONDITIONS
Official Title
The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 63 18
- Planned primary total knee replacement
- Planned neuraxial anesthesia
- Signed written informed consent form
You will not qualify if you...
- Urgent surgery
- Planned revision total knee replacement
- Known allergic reaction to anesthetics
- Confirmed localized infection at the puncture sites
- Confirmed localized tumor at the puncture sites
- Peripheral neuropathy of the lower extremities
- Parkinson's disease
- Previously enrolled in this trial
AI-Screening
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Trial Site Locations
Total: 1 location
1
Clinical Hospital on Yauza
Moscow, Russia, 111033
Actively Recruiting
Research Team
V
Valery Likhvantsev
CONTACT
L
Levan Berikashvili
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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