Actively Recruiting
Impact of Sinus Surgery on Individuals With Cystic Fibrosis
Led by University of California, Los Angeles · Updated on 2026-04-22
170
Participants Needed
9
Research Sites
343 weeks
Total Duration
On this page
Sponsors
U
University of California, Los Angeles
Lead Sponsor
C
Cystic Fibrosis Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.
CONDITIONS
Official Title
Impact of Sinus Surgery on Individuals With Cystic Fibrosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects between 18 and 99 years old (subjects over 89 recorded as 89)
- Diagnosed with cystic fibrosis by genetic testing combined with clinical assessment and/or sweat chloride
- Diagnosed with chronic rhinosinusitis according to multidisciplinary sinusitis guidelines
- Chronic rhinosinusitis symptoms persisting beyond initial medical treatment
- Counseled for endoscopic sinus surgery and ongoing medical therapy with patient choosing preferred treatment
You will not qualify if you...
- Underwent endoscopic sinus surgery in the past 12 months
- Will receive follow-up care at non-participating institutions
- Unable to complete follow-up surveys
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 9 locations
1
University of California, Los Angeles
Los Angeles, California, United States, 90095
Actively Recruiting
2
Stanford University
Stanford, California, United States, 94305
Actively Recruiting
3
University of Colorado
Aurora, Colorado, United States, 80045
Actively Recruiting
4
National Jewish Health
Denver, Colorado, United States, 80206
Actively Recruiting
5
University of North Carolina
Chapel Hill, North Carolina, United States, 27514
Actively Recruiting
6
Oregon Health Science University
Portland, Oregon, United States, 97239
Actively Recruiting
7
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
8
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232
Actively Recruiting
9
University of Utah
Salt Lake City, Utah, United States, 84132
Actively Recruiting
Research Team
D
Daniel M Beswick, MD
CONTACT
M
Marlene Florian
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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