Actively Recruiting
Impact of Sleep Duration on Immune Balance in Urban Children With Asthma
Led by Rhode Island Hospital · Updated on 2025-09-22
204
Participants Needed
1
Research Sites
219 weeks
Total Duration
On this page
Sponsors
R
Rhode Island Hospital
Lead Sponsor
B
Brown University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Urban children with asthma are at high risk for short sleep, due to an environment that jeopardizes both sleep and asthma management. Further, urban children with asthma suffer from altered immune balance, a key biological process contributing to individual differences in asthma morbidity and sleep health. In the proposed research, the researchers will examine the effects of shortened and recovery sleep on immune balance and associated changes in lung function in urban children with allergic asthma through an experimental design.
CONDITIONS
Official Title
Impact of Sleep Duration on Immune Balance in Urban Children With Asthma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged 7 to 11 years
- Physician-diagnosed asthma confirmed by parent and pediatrician
- Current persistent asthma with a prescription for an asthma controller medicine
- Obtains 9.0 to 11.0 hours of sleep per 24-hour day in the past month
- Positive allergy skin test performed at clinic visit
- Lives and attends school in specified urban areas of Rhode Island or Massachusetts
- Has a primary caregiver who speaks English
You will not qualify if you...
- No asthma diagnosis
- No use of asthma controller medication
- Severe persistent asthma that is poorly controlled
- Additional pulmonary disease, medical conditions, or immune deficiency disorders
- Use of systemic steroids within 30 days before screening
- Asthma-related emergency department visit or hospitalization in past 90 days
- Marked developmental delay, psychiatric, academic, behavioral problems, or learning disabilities
- Tanner stage 3 to 5 of pubertal development
- Diagnosed ADHD or use of stimulant medications for ADHD
- Apnea-Hypoxia Index greater than 5 indicating sleep disordered breathing
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Rhode Island Hospital
Providence, Rhode Island, United States, 02903
Actively Recruiting
Research Team
D
Daphne Koinis-Mitchell, PhD
CONTACT
S
Sheryl J Kopel, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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