Actively Recruiting
Impact of Stress on Cardiovascular Events in Patients with Peripheral Arterial Disease
Led by University Hospital, Essen · Updated on 2025-03-20
300
Participants Needed
1
Research Sites
192 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Essen
Lead Sponsor
U
Universität Duisburg-Essen
Collaborating Sponsor
AI-Summary
What this Trial Is About
Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality worldwide. Patients with peripheral arterial disease are at increased risk suffering from major adverse cardiac and limb events. Acute and chronic stress affect the cardiovascular system. Long-term negative stressors lead to cardiovascular diseases and can aggravate already existing cardiovascular diseases. However, current guidelines on cardiovascular disease prevention highlight stress as a cardiovascular risk factor there is a lack of consensus about the definition and measurement of stress. The aim of the proposed trial is to evaluate different stress measuring methods in patients with PAD depending on the occurrence of cardiovascular events.
CONDITIONS
Official Title
Impact of Stress on Cardiovascular Events in Patients with Peripheral Arterial Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of lower extremity peripheral arterial disease (PAD) based on one or more of the following:
- Limb bypass surgery
- Aorta-femoral bypass surgery
- Percutaneous transluminal angioplasty revascularization of the iliac or infrainguinal arteries
- Limb or foot amputation for arterial vascular disease
- Intermittent claudication plus either ankle brachial index (ABI) less than 0.90 or peripheral artery stenosis (≥50%) documented by angiography or duplex ultrasound
- Carotid revascularization or asymptomatic carotid artery stenosis of at least 50% diagnosed by duplex ultrasound or angiography
You will not qualify if you...
- Atrial fibrillation
- High premature ventricular contractions burden
- Pacemaker with constant ventricular pacing
- Use of antiarrhythmic drugs class I or III
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen
Essen, Germany, 45147
Actively Recruiting
Research Team
J
Julia Lortz, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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