Wellness Program to Improve Quality of Life for Adults with Neuromyelitis Optica Spectrum Disorder Randomized Study of Behavioral and Physical Health Interventions

What this Trial Is About

Researchers are evaluating whether a structured wellness program can improve the quality of life for adults living with Neuromyelitis Optica Spectrum Disorder NMOSD. This pilot randomized controlled trial will compare immediate versus delayed start of a multi-modal wellness program tailored to NMOSD patients, involving physical therapists, dietitians, social workers, nurse practitioners, and cognitive therapists. The study aims to assess quality of life using the MS-Quality of Life-54 tool as the primary measurement. Participants will be randomly assigned to either begin the wellness program immediately or after a 6-month delay. The program includes comprehensive evaluations by a dietician, social worker, physical therapist, nurse practitioner, and behavioral neuropsychologist. Follow-up sessions will monitor progress and challenges. After the initial 6-month period, participants may join a one-year extension study with additional wellness interventions and bi-monthly behavioral counseling. Throughout the study, participants will complete surveys and objective assessments at baseline, 12 weeks, 6 months, 12 months, and 18 months to evaluate quality of life, vision, mobility, exercise habits, diet adherence, and motor and vision function. These measures help researchers understand the programs impact and its sustainability over time. The total study duration for those in the extension phase can be up to 18 months.

Impact of a Structured Wellness Behavioral Intervention on Quality of Life in NMOSD