Actively Recruiting
The Impact on Survival of Neo-adjuvant Transarterial Chemoinfusion (TAI) for Patients With Hepatocellular Carcinoma And Portal Vein Tumor Thrombosis (PVTT) Who Underwent Hepatectomy : A Random, Controlled, Stage III Clinical Trial.
Led by Sun Yat-sen University · Updated on 2017-12-11
230
Participants Needed
1
Research Sites
678 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To compare the impact on survival of neo-adjuvant TAI for patients with HCC and PVTT who underwent hepatectomy.
CONDITIONS
Official Title
The Impact on Survival of Neo-adjuvant Transarterial Chemoinfusion (TAI) for Patients With Hepatocellular Carcinoma And Portal Vein Tumor Thrombosis (PVTT) Who Underwent Hepatectomy : A Random, Controlled, Stage III Clinical Trial.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years old
- ECOG performance status of 0 or 1
- Confirmed hepatocellular carcinoma by pathological examination or EASL/AASLD criteria
- No prior treatment for the tumor
- Tumor and tumor thrombosis estimated to be removable together by surgery
- No distant metastasis
- Laboratory tests meeting specific criteria: neutrophil count ≥2.0×10⁹/L; hemoglobin ≥100 g/L; platelet count ≥75×10⁹/L; serum albumin ≥35 g/L; total bilirubin less than twice the upper limit of normal; ALT and AST less than three times the upper limit of normal; serum creatinine less than 1.5 times the upper limit of normal; prothrombin time within 4 seconds above the upper limit of normal; INR ≤2.2
- Signed informed consent
You will not qualify if you...
- Unable to tolerate transarterial chemoinfusion or surgery
- Presence of distant metastasis
- History of other malignancies
- Allergy to related drugs
- Previous organ transplantation
- Previous treatment for the tumor, including interferon
- Known HIV infection
- History of drug or alcohol abuse
- Gastrointestinal hemorrhage or cardiac/brain vascular events within the past 30 days
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cancer Center of Sun Yat-Sen University
Guangzhou, Guangdong, China, +86
Actively Recruiting
Research Team
S
Shaohua Li, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here