Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05408117

Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color

Led by Melissa Pugliano-Mauro · Updated on 2025-07-08

34

Participants Needed

3

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmentation and scarring in patients of skin of color. Through a split-wound study design, patients undergoing standard elliptical excisions at least 3 cm in length will receive each suture type. Measurements of dyspigmentation and scarring will be made at 7 days (for the head and neck), 10 days (for the trunk and extremities), and 3 months for all locations.

CONDITIONS

Official Title

Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Undergoing dermatologic surgery with planned elliptical excision of 3 cm or greater
  • Able to give informed consent
  • Able to return for 3 month follow up
  • New Immigration Scale (NIS) skin color 4 or greater
Not Eligible

You will not qualify if you...

  • High-tension wound closures not suitable for 5-0 simple running epidermal sutures
  • Known allergy to suture materials
  • Pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

UPMC Presbyterian

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

2

UPMC St. Margaret

Pittsburgh, Pennsylvania, United States, 15215

Actively Recruiting

3

UPMC Shadyside Place

Pittsburgh, Pennsylvania, United States, 15232

Actively Recruiting

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Research Team

M

Melissa Pugliano-Mauro, MD

CONTACT

J

Jeffrey M Plowey, MS, ASCP(HTL)

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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