Actively Recruiting

Phase 2
Age: 18Years +
FEMALE
Healthy Volunteers
NCT04597372

Impact of Tamsulosin on Post-Operative Urinary Retention Following Pelvic Reconstructive Surgery

Led by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Updated on 2026-03-20

154

Participants Needed

1

Research Sites

264 weeks

Total Duration

On this page

Sponsors

A

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Lead Sponsor

J

Johns Hopkins University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The objective of the study is to determine the effectiveness of postoperative Tamsulosin in reducing the duration of acute postoperative urinary retention (POUR) following pelvic reconstructive surgery through a double blind, randomized placebo-controlled trial.

CONDITIONS

Official Title

Impact of Tamsulosin on Post-Operative Urinary Retention Following Pelvic Reconstructive Surgery

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Willing and able to provide informed consent
  • Diagnosed with postoperative urinary retention defined by a failed retrograde voiding trial prior to hospital discharge
  • Ability to speak and read English
  • Able to tolerate pill ingestion
Not Eligible

You will not qualify if you...

  • Allergy or intolerance to Tamsulosin or sulfa drugs
  • History of urinary retention before surgery defined by preoperative post-void residual over 150 mL
  • Current use of alpha antagonist medication for hypertension
  • Severe dementia
  • End stage kidney or liver disease
  • History of severe heart failure or major cardiovascular event within the last 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

West Penn Hospital

Pittsburgh, Pennsylvania, United States, 15224

Actively Recruiting

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Research Team

L

Lindsay Turner

CONTACT

A

AHN Clinical Trials Contact

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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