Actively Recruiting
IMPACT Trial: Intervention to iMProve AdherenCe Equitably
Led by Columbia University · Updated on 2026-05-06
350
Participants Needed
1
Research Sites
265 weeks
Total Duration
On this page
Sponsors
C
Columbia University
Lead Sponsor
N
National Institute on Minority Health and Health Disparities (NIMHD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
To determine the efficacy of a multicomponent adherence intervention among participants with early-stage breast cancer on endocrine therapy and at least one oral cardiovascular disease (CVD) medication on adherence to endocrine therapy and to CVD medication at 24 weeks assessed by self-report using the Domains of Subjective Extent (DOSE)-Nonadherence questionnaire and also by pharmacy fill data assessed in the electronic health record (EHR).
CONDITIONS
Official Title
IMPACT Trial: Intervention to iMProve AdherenCe Equitably
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women or men age >18 years
- Diagnosed with stage I-III breast cancer prescribed endocrine therapy
- Within 3 years of the end of early active treatment such as surgery, chemotherapy (excluding HER2-directed therapy), or radiation
- Prescribed at least one antihypertensive or statin medication for cardiovascular disease prevention
- Self-report of some nonadherence to endocrine therapy or cardiovascular disease medication on the DOSE-Nonadherence questionnaire
You will not qualify if you...
- Evidence of breast cancer recurrence
- Non-English or non-Spanish speaking
- Not cognitively able to complete study requirements
- Do not follow with a primary care provider or cardiologist within the New York Presbyterian Health system's Epic electronic health record
- Unable to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Columbia University Medical Center
New York, New York, United States, 10032
Actively Recruiting
Research Team
R
Research Nurse Navigator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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